Evidence map›Paper›PMID 35288617›Full record

ArticleScientific reports2022

A data driven approach to identify trajectories of prenatal alcohol consumption in an Australian population-based cohort of pregnant women.

Evelyne Muggli, Stephen Hearps, Jane Halliday, Elizabeth J Elliott, Anthony Penington, Deanne K Thompson, Alicia Spittle, Della A Forster, Sharon Lewis, Peter J Anderson

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Impact of active phase duration on neonatal and maternal adverse outcomes: A systematic analysis of parity stratification, body mass index interaction, and predictive modeling in a retrospective cohort.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Evelyne MuggliMurdoch Children's Research Institute, Parkville, VIC, Australia.
Stephen HearpsMurdoch Children's Research Institute, Parkville, VIC, Australia.
Jane HallidayMurdoch Children's Research Institute, Parkville, VIC, Australia.
Elizabeth J ElliottChild and Adolescent Health, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Anthony PeningtonMurdoch Children's Research Institute, Parkville, VIC, Australia.
Deanne K ThompsonMurdoch Children's Research Institute, Parkville, VIC, Australia.
Alicia SpittleMurdoch Children's Research Institute, Parkville, VIC, Australia.
Della A ForsterJudith Lumley Centre, School of Nursing and Midwifery, SHE College, La Trobe University, Bundoora, VIC, Australia.
Sharon LewisMurdoch Children's Research Institute, Parkville, VIC, Australia.
Peter J AndersonMurdoch Children's Research Institute, Parkville, VIC, Australia. peter.j.anderson@monash.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate information on dose, frequency and timing of maternal alcohol consumption is critically important when investigating fetal risks from prenatal alcohol exposure. Identification of distinct alcohol use behaviours can also assist in developing directed public health messages about possible adverse child outcomes, including Fetal Alcohol Spectrum Disorder. We aimed to determine group-based trajectories of time-specific, unit-level, alcohol consumption using data from 1458 pregnant women in the Asking Questions about Alcohol in Pregnancy (AQUA) longitudinal study in Melbourne, Australia. Six alcohol consumption trajectories were identified incorporating four timepoints across gestation. Labels were assigned based on consumption in trimester one and whether alcohol use was continued throughout pregnancy: abstained (33.8%); low discontinued (trimester one) (14.4%); moderate discontinued (11.7%); low sustained (13.0%); moderate sustained (23.5%); and high sustained (3.6%). Median weekly consumption in trimester one ranged from 3 g (low discontinued) to 184 g of absolute alcohol (high sustained). Alcohol use after pregnancy recognition decreased dramatically for all sustained drinking trajectories, indicating some awareness of risk to the unborn child. Further, specific maternal characteristics were associated with different trajectories, which may inform targeted health promotion aimed at reducing alcohol use in pregnancy.

Indexed as

Pregnant PeoplePrenatal Exposure Delayed EffectsAlcohol DrinkingAustraliaEthanolFemaleHumansLongitudinal StudiesPregnancyEthanol

Identifiers

PMID35288617
PMCPMC8921195

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.