ArticleScientific reports2022
Persistent post-concussive syndrome in children after mild traumatic brain injury is prevalent and vastly underdiagnosed.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of brain structural and functional alterations in pediatric mild traumatic brain injury.Frontiers in neuroscience · 2026Pooled it
- Depressive Symptoms in Individuals With Persistent Postconcussion Symptoms: A Systematic Review and Meta-Analysis.JAMA network open · 2022Pooled it
- Hyperbaric oxygen therapy in children with post-concussion syndrome improves cognitive and behavioral function: a randomized controlled trial.Scientific reports · 2022Trial
- Knowledge and practice of evidence-based mild traumatic brain injury guidelines among physicians providing emergency and trauma care in Israel.Israel journal of health policy research · 2026Article
- The Integrated Effect of Physical Activity and Sleep Problems on Concussion Symptom Resolution.Journal of sport rehabilitation · 2026Article
- Current Research on the Diagnosis and Management of Persistent Post-Traumatic Headache.Current pain and headache reports · 2026Review
- A multi-national cross-sectional exploration of rehabilitation services for children and young people following brain injury in low and middle income countries.BMC public health · 2025Article
- Volumetric and Diffusion Tensor Imaging Abnormalities Are Associated With Behavioral Changes Post-Concussion in a Youth Pig Model of Mild Traumatic Brain Injury.NMR in biomedicine · 2025Article
- Quality of Life after Brain Injury in children aged six and seven years (QOLIBRI-KIDDY) - development and scale analysis of the first disease-specific self-report instrument for young children after traumatic brain injury.Journal of patient-reported outcomes · 2025Article
- Predictors of persisting symptoms after concussion in children following a traumatic brain injury: a longitudinal retrospective cohort study.BMJ paediatrics open · 2025Article
- Trajectories of intrinsic connectivity one year post pediatric mild traumatic brain injury: Neural injury superimposed on neurodevelopment.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Article
- Concussion and the Autonomic, Immune, and Endocrine Systems: An Introduction to the Field and a Treatment Framework for Persisting Symptoms.Journal of personalized medicine · 2025Review
- Hyperbaric oxygen therapy improves post-concussion symptoms in adults with childhood traumatic brain injury: a retrospective cohort study.Frontiers in neurology · 2025Article
- Mental health trajectory throughout high school football career: a four-year prospective cohort study.Frontiers in psychiatry · 2025Article
- A Comparative Neuroimaging Review of Repetitive Head Impacts and Mild Traumatic Brain Injury from Pediatrics to Professionals.Neurotrauma reports · 2025Review
- Article
- Neuroprotective effect of triptolide on neuronal inflammation in rats with mild brain injury.IBRO neuroscience reports · 2024Article
- Role of nonpharmacological concussion management in children: systematic review of randomized controlled trials.Clinical and experimental pediatrics · 2024Article
- American Headache Society white paper on treatment of post-traumatic headache from concussion in youth.Headache · 2024Article
- Final Validation of the Quality of Life after Brain Injury for Children and Adolescents (QOLIBRI-KID/ADO) Questionnaire.Children (Basel, Switzerland) · 2024Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Data on epidemiology and prognosticators of persistent post-concussion syndrome (PPCS) after mild traumatic brain injury (mTBI) in the pediatric population is scarce. The aim of this study was to evaluate the prevalence of PPCS in children after mTBI and to identify clinical variables in children who are at high risk for developing PPCS. A multicenter, retrospective matched cohort in which PPCS symptoms were evaluated in children 8-15-year-old, 6-60 months after being admitted to the emergency department because of mTBI. The control group included children admitted to the emergency department because of uncomplicated distal radius fractures. The children's guardians were interviewed for the presence of PPCS symptoms using the "Rivermead Post-Concussion Questionnaire". A multivariable logistic regression model was used to identify predictors of PPCS. Two-hundred and five children were included in the mTBI group and 205 in the control. The median time from the injury was 33.5 months in the mTBI group and 33.8 in the control. The prevalence of PPCS in the mTBI group was 25.3% and PPCS like symptoms in the control was 2.4%, p < 0.001. Within the 6-60 months period, the PPCS prevalence was not influenced by the time that elapsed from the injury. In the mTBI group, motor vehicle accidents and adolescence were found to be risk factors for PPCS. PPCS is underdiagnosed in the pediatric population and 25% of children admitted to the ED due to mTBI may suffer from PPCS. Screening guidelines should be implemented to identify and properly treat these children.
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