Evidence map›Paper›PMID 35288592›Full record

ArticleScientific reports2022

MIR17HG polymorphisms contribute to high-altitude pulmonary edema susceptibility in the Chinese population.

Lining Si, Haiyang Wang, Yahui Jiang, Yun Yi, Rong Wang, Qifu Long, Yanli Zhao

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. B2M is a Biomarker Associated With Immune Infiltration In High Altitude Pulmonary Edema.Combinatorial chemistry & high throughput screening · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lining SiDepartment of Critical-Care Medicine, Affiliated Hospital of Qinghai University, Xining, 810001, Qinghai, China.
Haiyang WangDepartment of Diabetes of Traditional Chinese Medicine, Qinghai Red Cross Hospital, Xining, 810001, Qinghai, China.
Yahui JiangMedical College, Qinghai University, No. 29 Tongren Road, Xining, 810001, Qinghai, China.
Yun YiMedical College, Qinghai University, No. 29 Tongren Road, Xining, 810001, Qinghai, China.
Rong WangMedical College, Qinghai University, No. 29 Tongren Road, Xining, 810001, Qinghai, China.
Qifu LongMedical College, Qinghai University, No. 29 Tongren Road, Xining, 810001, Qinghai, China.
Yanli ZhaoMedical College, Qinghai University, No. 29 Tongren Road, Xining, 810001, Qinghai, China. yanli_2000@163.com.
Qinghai University · CNQinghai Red Cross Hospital · CNQinghai University Affiliated Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-altitude pulmonary edema (HAPE) is a common acute altitude sickness. This study was designed to investigate the effect of MIR17HG polymorphisms on HAPE risk in the Chinese population. The Agena MassARRAY platform was used to genotype six single-nucleotide polymorphisms (SNPs) in the MIR17HG gene in 244 HAPE patients and 243 non-HAPE controls. The odds ratio (OR) and 95% confidence interval were used to evaluate the association between each MIR17HG polymorphisms and the risk of HAPE under a polygenetic model. Statistical analysis was performed using the χ

Indexed as

Altitude SicknessPulmonary EdemaAltitudeCase-Control StudiesChinaFemaleGenetic Predisposition to DiseaseHumansHypertension, PulmonaryMaleRNA, Long NoncodingMIR17HG, humanRNA, Long Noncoding

Identifiers

PMID35288592
PMCPMC8921515
OpenAlexW4220661243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.