Evidence map›Paper›PMID 35288575›Full record

ArticleNature communications2022

Quantifying and comparing radiation damage in the Protein Data Bank.

Kathryn L Shelley, Elspeth F Garman

Abstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Separating the effects of temperature and absorbed X-ray dose on unit-cell volume.Acta crystallographica. Section D, Structural biology · 2026
    Article
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  5. Measurement of atomic scattering factors by cryoelectron microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  11. Dirhodium Tetraacetate Binding to Lysozyme at Body Temperature.International journal of molecular sciences · 2025
    Article
  12. Extending the reach of single-particle cryoEM.Current opinion in structural biology · 2025
    Review
  13. bioRxiv : the preprint server for biology · 2025
    Article
  14. Article
  15. A database overview of metal-coordination distances in metalloproteins.Acta crystallographica. Section D, Structural biology · 2024
    Article
  16. Identifying and avoiding radiation damage in macromolecular crystallography.Acta crystallographica. Section D, Structural biology · 2024
    Article
  17. Article
  18. Guide to serial synchrotron crystallography.Current research in structural biology · 2024
    Review
  19. Article
  20. The CCP4 suite: integrative software for macromolecular crystallography.Acta crystallographica. Section D, Structural biology · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Kathryn L ShelleyDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, United Kingdom. kathryn.l.shelley@gmail.com.ORCID http://orcid.org/0000-0003-2206-7778
Elspeth F GarmanDepartment of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, United Kingdom. elspeth.garman@bioch.ox.ac.uk.ORCID http://orcid.org/0000-0001-8329-5665

Funding

Biotechnology and Biological Sciences Research Council
6 · The paper itself

Abstract

Radiation damage remains one of the major bottlenecks to accurate structure solution in protein crystallography. It can induce structural and chemical changes in protein crystals, and is hence an important consideration when assessing the quality and biological veracity of crystal structures in repositories like the Protein Data Bank (PDB). However, detection of radiation damage artefacts has traditionally proved very challenging. To address this, here we introduce the B

Indexed as

ProteinsCrystallography, X-RayDatabases, ProteinModels, MolecularProtein ConformationProteins

Identifiers

PMID35288575
PMCPMC8921271

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.