ReviewBiological psychology2022
The psychophysiology of the sigh: I: The sigh from the physiological perspective.
Review in Biological psychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Tolerability, Safety and Effectiveness of Sigh Introduction During Non-Invasive Mechanical Ventilation Cycles in Patients With Amyotrophic Lateral Sclerosis.European journal of neurology · 2026Trial
- Circuit Mechanisms Underlying the Contribution of Leptin Receptor-Expressing Neurons in the Nucleus Tractus Solitarius to Ventilatory Homeostasis.Neuroscience bulletin · 2026Article
- Astrocyte activation in the ventrolateral medulla modulates breathing and arousal states.Nature communications · 2026Article
- Respiratory-Limbic Coupling via a Thalamic Circuit Alleviates Anxiety.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Neonatal inflammation induces lasting sex- and region-dependent microglia activation and sex-dependent impairments in chemoreflexes.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- Dissecting Cardiovascular Responses to a Fixed-Interval Volitional Sighing Protocol Using a Mixed Modeling Approach.Psychophysiology · 2026Article
- Sighs Shape Respiratory Variability and Pupil Dynamics and Adapt to Sustained Attention Demands.Psychophysiology · 2026Article
- Review
- An objective method to detect sighs during cardio-pulmonary exercise testing.Scientific reports · 2025Article
- It's About Time-Breathing Dynamics Modulate Emotion and Cognition.Psychophysiology · 2025Article
- Functional modulation of retrotrapezoid neurons drives fentanyl-induced respiratory depression.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Neuroanatomical and neurochemical organization of brainstem and forebrain circuits involved in breathing regulation.Journal of neurophysiology · 2025Review
- Inspiratory and sigh breathing rhythms depend on distinct cellular signalling mechanisms in the preBötzinger complex.The Journal of physiology · 2024Article
- Cervical spinal cord hemisection impacts sigh and the respiratory reset in male rats.Physiological reports · 2024Article
- A comparative examination of morphine and fentanyl: unravelling the differential impacts on breathing and airway stability.The Journal of physiology · 2023Article
- Sighs, Stops, and Swings: Breathing in Preterm Neonates.Indian journal of pediatrics · 2023Article
- Co-activation of the diaphragm and external intercostal muscles through an adaptive closed-loop respiratory pacing controller.Frontiers in rehabilitation sciences · 2023Article
- The psychophysiology of the sigh: II: The sigh from the psychological perspective.Biological psychology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Breathing is composed of multiple, distinct behaviors that are bidirectionally regulated through autonomic and voluntary mechanisms. One behavioral component is the sigh, which serves distinct physiological and psychological roles. In two accompanying reviews we will discuss these roles. The present review focuses on the physiological function, where sighs play a critical role in controlling lung compliance by preventing the collapse of alveoli. Implicated in the generation of sighs and normal breathing is the preBötzinger Complex, a rhythmogenic network in the medulla. Although sighs and normal inspiration are generated within the same network, they show distinct temporal characteristics. While sighs occur every few minutes, normal breathing is generated in the range of seconds. Both are differentiated by distinct modulatory and synaptic mechanisms, and recent evidence indicates that these mechanisms are regulated by inputs from different regions of the brain. An important modulator of sighs is hypoxia, implicating sighs in the arousal response.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.