Evidence map›Paper›PMID 35288189›Full record

ArticleThe Journal of biological chemistry2022

Nitric oxide precipitates catastrophic chromosome fragmentation by bolstering both hydrogen peroxide and Fe(II) Fenton reactants in E. coli.

Pooja Agashe, Andrei Kuzminov

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pooja AgasheDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Andrei KuzminovDepartment of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA. Electronic address: kuzminov@illinois.edu.
University of Illinois Urbana-Champaign · US

Funding

Synergistic toxicity of reactive oxygen speciesR01GM132484 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KUZMINOV, ANDREI · 2020 to 2023
$1.2M
NIGMS NIH HHS R01 GM132484
6 · The paper itself

Abstract

Immune cells kill invading microbes by producing reactive oxygen and nitrogen species, primarily hydrogen peroxide (H

Indexed as

ChromosomesEscherichia coliHydrogen PeroxideNitric OxideEnzyme InhibitorsFerric CompoundsFerrous CompoundsHydroxyl RadicalNADOxidation-ReductionEnzyme InhibitorsFerric CompoundsFerrous CompoundsHydrogen PeroxideHydroxyl RadicalNADNitric Oxidecatalasedouble-strand DNA breaksferritinhydrogen peroxideiron metabolismnitric oxideoxidative stressperoxynitriterespiration

Identifiers

PMID35288189
PMCPMC9018393
OpenAlexW4221080582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.