Evidence map›Paper›PMID 35287987›Full record

ArticleVaccine2022

The impact of COVID-19 on routine pediatric vaccination delivery in Brazil.

Carolina Moura, Paul Truche, Lucas Sousa Salgado, Thiaro Meireles, Vitor Santana, Alexandra Buda, Aline Bentes, Fabio Botelho, David Mooney

Open access · greenAbstract read
In one paragraph

Article in Vaccine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Childhood vaccination coverage and socioeconomic inequalities in the Northern region of Brazil.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2026
    Article
  3. Article
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  6. Quinolone Resistance and Zoonotic Potential ofAntibiotics (Basel, Switzerland) · 2025
    Article
  7. Is meningococcal B vaccination needed in the post-COVID-19 world?Biomedica : revista del Instituto Nacional de Salud · 2025
    Review
  8. Human papillomavirus vaccination access, coverage and dropout in the Federal District: a time series study, 2013-2023.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Full vaccination coverage with valid doses among the 2017 and 2018 live birth cohort in the Southeast region of Brazil.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2024
    Article
  14. Article
  15. Review
  16. Review
  17. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Carolina MouraFaculdade da Saúde e Ecologia Humana, FASEH, Vespasiano, MG, Brazil.
Paul TrucheProgram in Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA.
Lucas Sousa SalgadoUnião Educacional do Vale do Aço, UNIVAÇO, Departamento de Medicina, Ipatinga, MG, Brazil.
Thiaro MeirelesFaculdade de Medicina da Universidade de São Paulo, FMUSP, São Paulo, SP, Brazil.
Vitor SantanaFaculdade de Medicina da Universidade Federal de Minas Gerais, UFMG, Belo Horizonte, MG, Brazil.
Alexandra BudaProgram in Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA.
Aline BentesFaculdade de Medicina da Universidade Federal de Minas Gerais, Departamento de Infectologia Pediátrica, Belo Horizonte, MG, Brazil.
Fabio BotelhoHarvey E. Beardmore Division of Pediatric Surgery, Montreal Children's Hospital, Montreal, Canada.
David MooneyBoston Children's Hospital, Boston, MA, USA. Electronic address: david.mooney@childrens.harvard.edu.
Harvard University · USUniversidade Federal de Minas Gerais · BRBoston Children's Hospital · USHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRMontreal Children's Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChildhood vaccination rates have decreased significantly during the COVID-19 pandemic. The Brazilian immunization program, Programa Nacional de Imunização (PNI), is a model effort, achieving immunization rates comparable to high-income countries. This study aimed to evaluate the impact of the COVID-19 pandemic in pediatric vaccinations administered by the PNI, as a proxy of adherence to vaccinations during 2020.

methodsData on the number of vaccines administered to children under 10 years of age nationally and in each of Brazil's five regions were extracted from Brazil's federal health delivery database. Population adjusted monthly vaccination rates from 2015 through 2019 were determined, and autoregressive integrated moving average (ARIMA) models were used to forecast expected vaccinated rates in 2020. We compared the forecasts to reported vaccine administrations to assess adequacy of pediatric vaccine delivery during the COVID-19 pandemic.

resultsFrom January 2015 to February 2020, the average rate of vaccine administration to children was 53.4 per 100,000. After February 2020, this rate decreased to 50.4, a 9.4% drop compared to 2019 and fell outside of forecasted ranges in December 2020. In Brazil's poorest region, the North, vaccine delivery fell outside of the forecasted ranges earlier in 2020 but subsequently rebounded, meeting expected targets by the end of 2020. However, in Brazil's wealthiest South and Southeast regions, initial vaccine delivery fell and remained well below forecasted rates through the end of 2020.

conclusionIn Brazil, despite a model national pediatric vaccination program with an over 95% national coverage, vaccination rates decreased during the COVID-19 pandemic. Coordinated governmental efforts have ameliorated some of the decrease, but more efforts are needed to ensure continued protection from preventable communicable diseases for children globally.

Indexed as

COVID-19BrazilChildHumansImmunization ProgramsPandemicsVaccinationChild HealthHealth inequityHealth policyVaccination

Identifiers

PMID35287987
PMCPMC8885307
OpenAlexW4214628373

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.