Evidence map›Paper›PMID 35287666›Full record

ArticleBMC medical education2022

Chinese ICU physicians' knowledge of antibiotic pharmacokinetics/pharmacodynamics (PK/PD): a cross-sectional survey.

Wenchao Mao, Difan Lu, Jia Zhou, Junhai Zhen, Jing Yan, Li Li, Zhejiang Provincial Critical Care Clinical Research Group

Abstract read
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Article in BMC medical education, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Wenchao MaoDepartment of Critical Care Medicine, Zhejiang Hospital, Hangzhou, 310013, China.
Difan LuThe First Affiliated Hospital of Zhejiang University, Hangzhou, 310003, Zhejiang, China.
Jia ZhouDepartment of Critical Care Medicine, Zhejiang Hospital, Hangzhou, 310013, China.
Junhai ZhenDepartment of Critical Care Medicine, Zhejiang Hospital, Hangzhou, 310013, China.
Jing YanDepartment of Critical Care Medicine, Zhejiang Hospital, Hangzhou, 310013, China. yanjing2013@163.com.
Li LiDepartment of Critical Care Medicine, Zhejiang Hospital, Hangzhou, 310013, China. lilihbch@163.com.
Zhejiang Provincial Critical Care Clinical Research Group

Funding

Health Commission of Zhejiang Province Grant. WKJ-ZJ-2016, 2020KY007, and 2019ZB004
6 · The paper itself

Abstract

backgroundPatients with sepsis have a high mortality rate, accumulated evidences suggest that an optimal antibiotic administration strategy based on pharmacokinetics/pharmacodynamics (PK/PD) can improve the prognosis of septic patients. Therefore, we assessed Chinese intensive care unit (ICU) physicians' knowledge about PK/PD.

methodsIn December 2019, we designed a questionnaire focused on Chinese ICU physicians' knowledge about PK/PD and collected the questionnaires after 3 months. The questionnaire was distributed via e-mail and WeChat, and was distributed to ICU doctors in 31 administrative regions of China except Hong Kong, Macao and Taiwan. The passing score was corrected by the Angoff method, and the ICU physicians' knowledge about PK/PD was analysed accordingly.

resultsWe received a total of 1,309 questionnaires and retained 1,240 valid questionnaires. The passing score was 90.8, and the overall pass rate was 56.94%. The pass rate for tertiary and secondary hospitals was 59.07% and 37.19%, respectively. ICU physicians with less than 5 years of work experience and resident physician accounted for the highest pass rate, while those with between 5 to 10 years of work experience and attending accounted for the lowest pass rate. The majority of participants in the Chinese Critical Care Certified Course (5C) were from Jiangsu and Henan provinces, and they had the highest average scores (125.8 and 126.5, respectively). For Beijing and Shanghai, the average score was only 79.4 and 90.9, respectively.

conclusionsChinese ICU physicians' knowledge about PK/PD is unsatisfactory. Therefore, it is essential to strengthen ICU physicians' knowledge about PK/PD.

Indexed as

Anti-Bacterial AgentsPhysiciansChinaCross-Sectional StudiesHumansIntensive Care UnitsAnti-Bacterial AgentsAngoff methodAntibioticsIntensive care unitsPharmacodynamicsPharmacokineticsSepsis

Identifiers

PMID35287666
PMCPMC8920424

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