ArticleBMC ophthalmology2022
Changes of retinal structure and function in patients with internal carotid artery stenosis.
Article in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- The Relevance of Optical Coherence Tomography Angiography in Screening and Monitoring Hypertensive Patients with Carotid Artery Stenosis.Diagnostics (Basel, Switzerland) · 2025Article
- The Use of Retinal Imaging Including Fundoscopy, OCT, and OCTA for Cardiovascular Risk Stratification and the Detection of Subclinical Atherosclerosis.Current atherosclerosis reports · 2025Review
- Retinal Microangiopathy as a Marker of Coronary Atherosclerotic Heart Disease.International journal of general medicine · 2025Review
- Detection of macular and peripheral ocular microvascular changes after carotid artery revascularization using widefield SS-OCTA.Frontiers in medicine · 2025Article
- Effect of Premature Acute Coronary Syndrome on Ocular Hemodynamics.International journal of medical sciences · 2025Article
- Screening of Moyamoya Disease From Retinal Photographs: Development and Validation of Deep Learning Algorithms.Stroke · 2024Observational
- Application of the full-width-at-half-maximum image segmentation method to analyse retinal vascular changes in patients with internal carotid artery stenosis.Frontiers in cell and developmental biology · 2024Article
- Retinal Microvascular Changes in Internal Carotid Artery Stenosis.Journal of clinical medicine · 2023Article
- Comparison of Ophthalmic Artery Morphological Characteristics and Retinal Vessel Diameter for Identifying Ocular Ischemic Syndrome.Investigative ophthalmology & visual science · 2023Observational
- Length of Carotid Plaque Impacts Retinal Microvascular Densities of Carotid Artery Stenosis Patients.Translational vision science & technology · 2023Article
- A narrative review of retinal vascular parameters and the applications (Part II): Diagnosis in stroke.Brain circulationReview
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundTo investigate the structural and functional changes of the retina in patients with different degrees of internal carotid artery (ICA) stenosis.
methodsThis cross-sectional study included patients with varying degrees ICA stenosis. Clinical characteristics of 41 patients were collected after being divided into four groups according to the ICA stenosis indicated by computed tomographic angiography (Group 0: without ICA stenosis, Group 1: ipsilateral slight ICA stenosis, Group 2: ipsilateral moderate ICA stenosis, Group 3: ipsilateral severe ICA stenosis). Retinal vessel caliber (RVC) was measured quantitatively with the Integrative Vessel Analysis software. The retinal sensitivity was examined with the MP-3 microperimeter. The relationships among central retinal artery equivalent (CRAE), central retinal vein equivalent, arteriole to venule ratio (AVR), mean retinal sensitivity (MS) and ICA stenosis degree were analysed.
resultsThe CRAE in Group 3 were significantly smaller compared with Group 0, Group 1 and Group 2 (P < 0.001, P < 0.001, P = 0.002). Significant decrease was found between Group 3 with other groups in MS at fovea (P < 0.001, P < 0.001, P = 0.002). Moreover, there was a positive correlation found between MS and CRAE (Beta = 0.60, P < 0.001 at fovea; Beta = 0.64, P < 0.001 at 2 degree; Beta = 0.60, P < 0.001 at 4 degree; Beta = 0.55, P < 0.001 at 8 degree; Beta = 0.53, P < 0.001 at 12 degree).
conclusionsThe present study revealed smaller CRAE and AVR in ipsilateral severe ICA stenosis patients. And the MS decreased in patients with severe ICA stenosis. In addition, MS had a positive correlation with CRAE.
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