Evidence map›Paper›PMID 35287542›Full record

ArticleBioengineered2022

The double homeobox a pseudogene 8 accelerates cell proliferation, migration, and invasion in colon cancer.

Shengxun Mao, Zhaohong Mo, Runxin Wu, Bin Lai, Zhiyong Zhou, Yi Song, Xi Ouyang, Xingen Zhu

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Shengxun MaoDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Zhaohong MoDepartment of Hepatobiliary Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Runxin WuZhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Bin LaiDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Zhiyong ZhouDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Yi SongDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Xi OuyangDepartment of Gastrointestinal Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Xingen ZhuDepartment of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Nanchang University · CNSecond Affiliated Hospital of Nanchang University · CNSun Yat-sen University · CNThird Affiliated Hospital of Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Double homeobox A pseudogene 8 (DUXAP8) is a known tumor promoter in several malignancies. Nonetheless, its function in colon cancer (CC) is indefinite. Herein, we explored the significance of DUXAP8 and its underlying mechanism in CC. Our data indicated that DUXAP8 was upregulated in CC, and it was related to advanced stages and lymph node metastases. Based on our Kaplan-Meier survival analysis, elevated DUXAP8 expression resulted in shorter patient overall survival (OS). Conversely, DUXAP8 silencing strongly suppressed cellular proliferation, migration and invasion

Indexed as

Colonic NeoplasmsMicroRNAsRNA, Long NoncodingAnimalsCell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticGenes, HomeoboxHumansMicePseudogeneslong non-coding RNA DUXAP8, humanMicroRNAsRNA, Long Noncodingcolon cancerDUXAP8invasionmigrationproliferation

Identifiers

PMID35287542
PMCPMC9161926
OpenAlexW4221066733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.