Evidence map›Paper›PMID 35286708›Full record

ArticleCerebellum (London, England)2023

Three-Dimensional Digital Reconstruction of the Cerebellar Cortex: Lobule Thickness, Surface Area Measurements, and Layer Architecture.

Junxiao Zheng, Qinzhu Yang, Nikos Makris, Kaibin Huang, Jianwen Liang, Chenfei Ye, Xiaxia Yu, Mu Tian, Ting Ma, Tian Mou and 3 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Cerebellum (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Junxiao ZhengSchool of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, Guangdong, China.
Qinzhu YangSchool of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, Guangdong, China.
Nikos MakrisCenter for Morphometric Analysis, Departments of Psychiatry, Neurology, A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Departments of Psychiatry and Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Kaibin HuangSchool of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, Guangdong, China.
Jianwen LiangSchool of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, Guangdong, China.
Chenfei YePengcheng Lab, Shenzhen, Guangdong, China.
Xiaxia YuSchool of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, Guangdong, China.
Mu TianSchool of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, Guangdong, China.
Ting MaPengcheng Lab, Shenzhen, Guangdong, China.
Tian MouSchool of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, Guangdong, China.
Wenlong GuoGuangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Ron KikinisDepartment of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Yi GaoSchool of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen, Guangdong, China. gaoyi@szu.edu.cn.
Shenzhen University Health Science Center · CNPeng Cheng Laboratory · CNBrigham and Women's Hospital · USGuangdong Provincial People's Hospital · CNHarbin Institute of Technology · CNMassachusetts General Hospital · US

Funding

Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI WESTIN, CARL-FREDRIK · 2012 to 2022
$20.9M
Image Guided Therapy Center - Ultrasound-based sensor system for the monitoring of COVID-19 patientsP41EB015898 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI TEMPANY, CLARE M · 2012 to 2021
$18.9M
TRD 3 - Enabling Technologies for Intraprocedural GuidanceP41EB028741 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI Nobuhiko Hata, CLARE M TEMPANY · 2021 to 2026
$10.7M
Lymph Node Quantification System for Multisite Clinical TrialsR01CA235589 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI GORDON J HARRIS, Ron Kikinis · 2019 to 2026
$4.5M
High Resolution, Comprehensive Atlases of the Human Brain MorphologyR01MH112748 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI BOUIX, SYLVAIN, KUBICKI, MAREK · 2018 to 2022
$4.1M
Mentoring and neuroimaging research on new targets for DBS in OCDK24MH116366 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI MAKRIS, NIKOLAOS · 2018 to 2022
$817k
Modulating Inhibitory Control Networks In Gambling Disorder With Theta Burst StimulationR21DA042271 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI CAMPRODON, JOAN A, MAKRIS, NIKOLAOS · 2017 to 2018
$439k
NCI NIH HHS R01 CA235589NIBIB NIH HHS P41 EB015898NIBIB NIH HHS P41 EB015902NIBIB NIH HHS P41 EB028741NIDA NIH HHS R21 DA042271NIMH NIH HHS K24 MH116366NIMH NIH HHS R01 MH112748
6 · The paper itself

Abstract

The cerebellum is ontogenetically one of the first structures to develop in the central nervous system; nevertheless, it has been only recently reconsidered for its significant neurobiological, functional, and clinical relevance in humans. Thus, it has been a relatively under-studied compared to the cerebrum. Currently, non-invasive imaging modalities can barely reach the necessary resolution to unfold its entire, convoluted surface, while only histological analyses can reveal local information at the micrometer scale. Herein, we used the BigBrain dataset to generate area and point-wise thickness measurements for all layers of the cerebellar cortex and for each lobule in particular. We found that the overall surface area of the cerebellar granular layer (including Purkinje cells) was 1,732 cm

Indexed as

Cerebellar CortexCerebellumHumansPurkinje CellsCerebellar cortical layers measurementsCerebellar cortical layers morphometryCerebellumLaminar thickness measurementsLobulesSurface area

Identifiers

PMID35286708
PMCPMC9470778
OpenAlexW4220995347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.