Evidence map›Paper›PMID 35286611›Full record

ArticleDermatology and therapy2022

Impact of Psoriatic Disease on Quality of Life: Interim Results of a Global Survey.

April Armstrong, Barbra Bohannan, Sicily Mburu, Ivette Alarcon, Torben Kasparek, Jihen Toumi, Susan Frade, Silvia Fernandez Barrio, Matthias Augustin

Open access · goldAbstract read
In one paragraph

Article in Dermatology and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

April ArmstrongDepartment of Dermatology, University of Southern California, Los Angeles, CA, USA. aprilarmstrong@post.harvard.edu.
Barbra BohannanPsoriasisförbundet, Stockholm, Sweden.
Sicily MburuInternational Federation of Psoriasis Associations, Stockholm, Sweden.
Ivette AlarconNovartis Pharma AG, Basel, Switzerland.
Torben KasparekNovartis Pharma AG, Basel, Switzerland.
Jihen ToumiNovartis, Middle East FZE, Dubai, United Arab Emirates.
Susan FradeNovartis Pharma AG, Basel, Switzerland.
Silvia Fernandez BarrioAsociación Para En Enfermo De Psoriasis, Buenos Aires, Argentina.
Matthias AugustinUniversity Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Novartis (Switzerland) · CHUniversity Medical Center Hamburg-Eppendorf · DEUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPsoriatic disease (PsD) is a chronic systemic disorder affecting numerous body areas, including skin and joints. Patients' perspectives regarding understanding their disease and dialogue with healthcare professionals (HCPs) on treatment strategies is becoming increasingly important in the holistic management of PsD. The study aim was to determine patients' understanding of the systemic nature of psoriasis and psoriatic arthritis (PsA) and the associated burden of living with these diseases. The relationship between patient and HCP was also evaluated.

methodsPsoriasis and Beyond: The Global Psoriatic Disease Survey was a cross-sectional, quantitative online survey, conducted in patients with moderate to severe plaque psoriasis with or without concomitant PsA. Here, we report interim analysis results.

resultsA total of 1678 respondents from 11 countries were included. Overall, 31% of patients with psoriasis reported concomitant PsA, 80% of whom considered their PsA severity as moderately or highly active. In total, 63% of patients had heard the term "psoriatic disease". Few patients were aware of psoriasis manifestations (PsA, 29%; axial symptoms, 18%) or comorbidities (obesity, 21%; cardiovascular disease, 18%). Among patients with psoriasis and concomitant PsA, 70% reported swollen and tender joints, especially of the finger(s) and/or toe(s). Most patients (84%) experienced stigma and discrimination and reported a negative impact of their disease on work, emotions, and relationships. Overall, 42% of patients had never discussed treatment goals with their HCP. Patients who were dissatisfied with their current treatment (psoriasis, 15%; psoriasis with PsA, 14%) reported incomplete relief of skin symptoms (57%) and joint symptoms (45%) as primary reasons for dissatisfaction.

conclusionsDespite many patients having heard the term "psoriatic disease", the majority were unaware of the systemic nature and increased risk of comorbidities associated with PsD. This interim analysis highlights the need for patient education, productive patient-HCP dialogue, and shared decision-making in optimal disease management.

Indexed as

Patients’ perspectivePsoriasisPsoriatic arthritisPsoriatic diseaseSurveySystemic inflammation

Identifiers

PMID35286611
PMCPMC8918421
OpenAlexW4220661976

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.