Evidence map›Paper›PMID 35286577›Full record

ReviewFolia microbiologica2022

Bacterial biofilms and their resistance mechanisms: a brief look at treatment with natural agents.

Fahimeh Nourbakhsh, Mahda Sadat Nasrollahzadeh, Amineh Sadat Tajani, Vahid Soheili, Farzin Hadizadeh

Abstract readReview
PubMed Publisher
In one paragraph

Review in Folia microbiologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Viability and Virulence ofMicroorganisms · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Nanotechnology in interventional cardiology: A state-of-the-art review.International journal of cardiology. Heart & vasculature · 2022
    Review
  15. Green Extracellular Synthesis of Silver Nanoparticles byMolecules (Basel, Switzerland) · 2022
    Article
  16. DNase inhibits early biofilm formation inFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fahimeh NourbakhshMedical Toxicology Research Centre, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahda Sadat NasrollahzadehDepartment of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Amineh Sadat TajaniDepartment of Pharmaceutical Control, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Vahid SoheiliDepartment of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. SoheiliV@mums.ac.ir.ORCID http://orcid.org/0000-0002-5047-797X
Farzin HadizadehDepartment of Pharmaceutical Control, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. HadizadehF@mums.ac.ir.
Mashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofilm is a complex community of microorganisms residing within a polysaccharide and/or protein matrix. Biofilm can be produced by several microorganisms, including various bacteria and fungi. Nowadays, the resistance of biofilm-growing cells to antimicrobials originated from the structural nature of biofilms, and phenotypic alteration of sessile cells is becoming a global issue. Bacterial biofilms are important in various aspects of human health, including chronic infections, dental plaque, and infection of indwelling medical devices such as catheters. They are also a major problem in other industries, including oil recovery, drinking water distribution, papermaking, metalworking, and food processing. Estimates indicate that more than 80% of infectious diseases are biofilm-derived. The aim of this study is to describe mechanisms of antibiotic resistance to provide a better perspective on how to manage it. Moreover, the current strategies for biofilm inhibition were described. Considering that plants are a valuable source of abundant natural chemicals to create prophylactic and therapeutic medicines against biofilm-based infections, significant natural compounds with anti-biofilm properties were highlighted. Finally, natural anti-biofilm compounds under clinical trial evaluation were summarized to provide a background for more extensive researches and assist in opening a new window to novel treatments.

Indexed as

Anti-Infective AgentsBiofilmsAnti-Bacterial AgentsBacteriaFungiHumansAnti-Bacterial AgentsAnti-Infective Agents

Identifiers

PMID35286577
OpenAlexW4220862278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.