ArticleBreast cancer research and treatment2022
Trends in surgical treatment of early-stage breast cancer reveal decreasing mastectomy use between 2003 and 2016 by age, race, and rurality.
Article in Breast cancer research and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.
- One Surgery, Two Solutions: A Systematic Review of Combined Autologous Breast Reconstruction and Lymphatic Surgery.Current oncology (Toronto, Ont.) · 2026Pooled it
- Yield of Surveillance Imaging After Mastectomy With or Without Reconstruction for Patients With Prior Breast Cancer: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- Does Multidisciplinary Clinic Impact Rates of Breast Conserving Therapy?Annals of surgical oncology · 2026Article
- What Patients See: Evaluating the Quality, Readability, and Ethnic Inclusivity of Online Resources for Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2026Article
- Impact of Socioeconomic Factors on Surgical Approach and Outcomes in Young Women with Breast Cancer.European journal of breast health · 2025Article
- COVID-19 impacts on the breast cancer care pathway among systemically marginalized communities in Ontario.Cancer causes & control : CCC · 2025Article
- Catchment area and cancer population health research through a novel population-based statewide database: a scoping review.JNCI cancer spectrum · 2024Article
- Big Data for Geriatric Oncology Research.North Carolina medical journal · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo examine trends in the surgical treatment of breast cancer by age, rurality, and among Black women in a populous, racially diverse, state in the Southeastern United States of America.
methodsWe identified women diagnosed with localized or regional breast cancer between 2003 and 2016 in the North Carolina Central Cancer Registry (n = 86,776). Using Joinpoint regression we evaluated the average annual percentage change in proportion of women treated with mastectomy versus breast-conserving surgery overall, by age group, among Black women, and for women residing in rural areas.
resultsOverall, the rate of mastectomy usage in the population declined 2.5% per year between 2003 and 2016 (95% CI - 3.2, - 1.7). Over this same time interval, breast-conserving surgery increased by 1.6% per year (95% CI 0.9, 2.2). These temporal trends in surgery were also observed among Black women and rural residing women. Trends in surgery type varied by age group: mastectomy declined over time among women > 50 years, but not among women aged 18-49 at diagnosis. DISCUSSION: In contrast to national studies that reported increasing use of mastectomy, we found declining mastectomy rates in the early 2000s in a Southern US state with a racially and geographically diverse population. These decreasing trends were consistent among key subgroups affected by cancer inequities, including Black and White rural women.
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