ArticleInsights into imaging2022
Quantitative measurements of esophageal varices using computed tomography for prediction of severe varices and the risk of bleeding: a preliminary study.
Article in Insights into imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Predictive performance of CT-based artificial intelligence for predicting variceal bleeding in portal hypertension: a systematic review and meta-analysis.Abdominal radiology (New York) · 2026Pooled it
- [A dual-center study of enhanced CT-based nomograms predicts spontaneous portosystemic shunts on initial hemorrhage from rupture of esophageal gastric varices in cirrhosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026Article
- Features on contrast-enhanced computed tomography for predicting recurrent esophageal variceal bleeding in patients with hepatocellular carcinoma.BMC gastroenterology · 2025Article
- Can "Attenuation Subtraction", a Computed Tomography Scan-Based Factor, be Used as a Predictor of High-Risk Esophageal Varices in Cirrhotic Patients? A Retrospective Cohort Study.Health science reports · 2025Article
- Predictive value of high-risk esophageal varices in cirrhosis based on dual-energy CT combined with clinical and serologic features.BMC medical imaging · 2025Article
- Precirrhotic Primary Biliary Cholangitis with Portal Hypertension: Bile Duct Injury Correlate.Gut and liver · 2024Article
- The impact of hepatic and splenic volumetric assessment in imaging for chronic liver disease: a narrative review.Insights into imaging · 2024Review
- 3D-Volumetric Shunt Measurement for Detection of High-Risk Esophageal Varices in Liver Cirrhosis.Journal of clinical medicine · 2024Article
- HCC portal hypertension imaging score derived from CT predicts re-bleeding and mortality after acute variceal bleeding.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- The role of computed tomography for the prediction of esophageal variceal bleeding: Current status and future perspectives.World journal of gastrointestinal endoscopy · 2023Review
- Computed tomography virtual oesophagography for the grading of oesophageal varices in cirrhotic liver disease patients with upper gastrointestinal endoscopic examination as the gold standard: a diagnostic validation study.Polish journal of radiology · 2023Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to assess whether the quantitative parameters of esophageal varices (EV) based on computed tomography (CT) can noninvasively predict severe EV and the risk of esophageal variceal bleeding (EVB).
methodsA total of 136 endoscopically confirmed EV patients were included in this retrospective study and were divided into a non-conspicuous (mild-to-moderate EV, n = 30) and a conspicuous EV group (severe EV, n = 106), a bleeding (n = 89) and a non-bleeding group (n = 47). EV grade (EVG), EV diameter (EVD), cross-sectional surface area (CSA), EV volume (EVV), spleen volume (SV), splenic vein (SNV), portal vein (PV), diameter of left gastric vein (DLGV), and the opening type of LGV were measured independently using 3D-slicer. Univariate and multivariate logistic analysis were used to determine the independent factors and the receiver operating characteristic (ROC) curves were performed to evaluate the diagnostic performance.
resultsThe difference of EVG, EVD, CSA, EVV, DLGV, SNV between the conspicuous and non-conspicuous EV group were statistically significant (p < 0.05), area under the curves (AUCs) of them for predicting severe EV were 0.72, 0.772, 0.704, 0.768, 0.707, 0.65, with corresponding sensitivities of 70.3%, 63.5%, 50%, 74.3%, 52.7%, 48.6%, specificities of 71.4%, 85.7%, 100%, 71.4%, 81%, 81%, respectively. EVG, CSA (odds ratio 3.258, 95% CI 1.597-6.647; 1.029, 95% CI 1.008-1.050) were found to be independent predictive factors. However, there was no significant difference of the included indices between the bleeding and non-bleeding group (p > 0.05).
conclusionsCT can be used as a noninvasive method to predict the severity of EV, which may reduce the invasive screening of endoscopy.
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