ArticlePloS one2022
Host species is linked to pathogen genotype for the amphibian chytrid fungus (Batrachochytrium dendrobatidis).
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Spillover dynamics and asynchronous temporal fluctuations in host density and competence drive fungal parasite persistence in multi-host, seasonal communities.The Journal of animal ecology · 2026Article
- Article
- Host Genus and Habitat Use Shape the Distribution ofEcology and evolution · 2026Article
- Boreal Toad Survival Varies by Degree of Attenuation and Adaptation of a Fungal Pathogen.EcoHealth · 2026Article
- Identification of Opportunistic Pathogens on the Skin of Salamanders for Use as Molecular Targets of a De Novo Design of Multitarget Anti-International journal of microbiology · 2026Article
- Synthesizing selection mosaic theory and host-pathogen theory to explain large-scale pathogen coexistence.Nature communications · 2025Article
- Microbial responses to antibiotics cryptically shift the direction of disease outcomes.Scientific reports · 2025Article
- Successful Transmission and Isolation of a Fungal Pathogen From Wild Frogs to a Captive Amphibian Model Species: Fine Scale Pathogen Genetic Diversity and Infection-Induced Changes in Skin Bacteria.Environmental microbiology · 2025Article
- Independent and interactive effects of disease and methylmercury on demographic rates across multiple amphibian populations.Scientific reports · 2025Article
- Do fungi look like macroparasites? Quantifying the patterns and mechanisms of aggregation for host-fungal parasite relationships.Proceedings. Biological sciences · 2025Article
- Landscape-scale drivers of spatial dynamics and genetic diversity in an emerging wildlife pathogen.Oecologia · 2024Article
- Do fungi look like macroparasites? Quantifying the patterns and mechanisms of aggregation for host-fungal parasite relationships.bioRxiv : the preprint server for biology · 2024Article
- Evolutionary ecology of host competence after a chytrid outbreak in a naive amphibian community.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Conserved Evolution of MHC Supertypes among Japanese Frogs Suggests Selection for Bd Resistance.Animals : an open access journal from MDPI · 2023Article
Corrections and comments
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Authors and funding
8 authors.
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Abstract
Host-pathogen specificity can arise from certain selective environments mediated by both the host and pathogen. Therefore, understanding the degree to which host species identity is correlated with pathogen genotype can help reveal historical host-pathogen dynamics. One animal disease of particular concern is chytridiomycosis, typically caused by the global panzootic lineage of the amphibian chytrid fungus (Batrachochytrium dendrobatidis, Bd), termed Bd-GPL. This pathogen lineage has caused devastating declines in amphibian communities around the world. However, the site of origin for the common ancestor of modern Bd-GPL and the fine-scale transmission dynamics of this lineage have remained a mystery. This is especially the case in North America where Bd-GPL is widespread, but disease outbreaks occur sporadically. Herein, we use Bd genetic data collected throughout the United States from amphibian skin swabs and cultured isolate samples to investigate Bd genetic patterns. We highlight two case studies in Pennsylvania and Nevada where Bd-GPL genotypes are strongly correlated with host species identity. Specifically, in some localities bullfrogs (Rana catesbeiana) are infected with Bd-GPL lineages that are distinct from those infecting other sympatric amphibian species. Overall, we reveal a previously unknown association of Bd genotype with host species and identify the eastern United States as a Bd diversity hotspot and potential site of origin for Bd-GPL.
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