Evidence map›Paper›PMID 35286190›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Genetics, leadership position, and well-being: An investigation with a large-scale GWAS.

Zhaoli Song, Wen-Dong Li, Xuye Jin, Junbiao Ying, Xin Zhang, Ying Song, Hengtong Li, Qiao Fan

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Genetic variant rs9848497 up-regulatesProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  5. Reply to Qiu et al.: Hunting for leadership "causal" genes: Mission possible?Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Zhaoli SongDepartment of Management and Organization, National University of Singapore, 119245, Singapore.ORCID 0000-0002-4553-0334
Wen-Dong LiDepartment of Management, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
Xuye JinDepartment of Statistics and Data Science, National University of Singapore, 117546, Singapore.
Junbiao YingDepartment of Statistics and Data Science, National University of Singapore, 117546, Singapore.
Xin ZhangDepartment of Management, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China.
Ying SongDepartment of Statistics and Data Science, National University of Singapore, 117546, Singapore.
Hengtong LiDepartment of Statistics and Data Science, National University of Singapore, 117546, Singapore.ORCID 0000-0002-3843-7174
Qiao FanCentre for Quantitative Medicine, Duke-NUS Medical School, 169857, Singapore.

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VII Core ProjectU01AG071448 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Allison E Aiello, Lauren M Gaydosh · 2021 to 2026
$40.2M
National Longitudinal Study of Adolescent to Adult Health (Add Health): Wave VI Cognition and Early Risk Factors for Dementia ProjectU01AG071450 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AIELLO, ALLISON E, HUMMER, ROBERT A · 2021 to 2025
$16.2M
NIA NIH HHS U01 AG071448NIA NIH HHS U01 AG071450NICHD NIH HHS P01 HD031921
6 · The paper itself

Abstract

SignificanceOur study presents the largest whole-genome investigation of leadership phenotypes to date. We identified genome-wide significant loci for leadership phenotypes, which are overlapped with top hits for bipolar disorder, schizophrenia, and intelligence. Our study demonstrated the polygenetic nature of leadership, the positive genetic correlations between leadership traits and a broad range of well-being indicators, and the unique association of leadership with well-being after accounting for genetic influences related to other socioeconomic status measures. Our findings offer insights into the biological underpinnings of leadership.

Indexed as

Genome-Wide Association StudySchizophreniaHumansLeadershipMultifactorial InheritancePhenotypegeneticsGWASleadershipmanagementwell-being

Identifiers

PMID35286190
PMCPMC8944770

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.