Evidence map›Paper›PMID 35286023›Full record

ArticleCurrent protocols2022

Design, Construction, and Implementation of a Magnetic Resonance Elastography Actuator for Research Purposes.

Emily Rose Triolo, Oleksandr Khegai, Efe Ozkaya, Nicholas Rossi, Akbar Alipour, Lazar Fleysher, Priti Balchandani, Mehmet Kurt

Abstract read
In one paragraph

Article in Current protocols, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emily Rose TrioloDepartment of Mechanical Engineering, University of Washington, Seattle, Washington.
Oleksandr KhegaiIcahn School of Medicine at Mount Sinai, Biomedical Engineering and Imaging Institute, New York, New York.
Efe OzkayaIcahn School of Medicine at Mount Sinai, Biomedical Engineering and Imaging Institute, New York, New York.
Nicholas RossiDepartment of Mechanical Engineering, Stevens Institute of Technology, Hoboken, New Jersey.
Akbar AlipourIcahn School of Medicine at Mount Sinai, Biomedical Engineering and Imaging Institute, New York, New York.
Lazar FleysherIcahn School of Medicine at Mount Sinai, Biomedical Engineering and Imaging Institute, New York, New York.
Priti BalchandaniIcahn School of Medicine at Mount Sinai, Biomedical Engineering and Imaging Institute, New York, New York.
Mehmet KurtDepartment of Mechanical Engineering, University of Washington, Seattle, Washington.

Funding

Cross-correlation of biomechanical, connectomic, and pathologic markers in Alzheimer's disease at 7T MRIR21AG071179 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BALCHANDANI, PRITI, KURT, MEHMET · 2020 to 2020
$473k
NIA NIH HHS R21 AG071179
6 · The paper itself

Abstract

Magnetic resonance elastography (MRE) is a technique for determining the mechanical response of soft materials using applied harmonic deformation of the material and a motion-sensitive magnetic resonance imaging sequence. This technique can elucidate significant information about the health and development of human tissue such as liver and brain, and has been used on phantom models (e.g., agar, silicone) to determine their suitability for use as a mechanical surrogate for human tissues in experimental models. The applied harmonic deformation used in MRE is generated by an actuator, transmitted in bursts of a specified duration, and synchronized with the magnetic resonance signal excitation. These actuators are most often a pneumatic design (common for human tissues or phantoms) or a piezoelectric design (common for small animal tissues or phantoms). Here, we describe how to design and assemble both a pneumatic and a piezoelectric MRE actuator for research purposes. For each of these actuator types, we discuss displacement requirements, end-effector options and challenges, electronics and electronic-driving requirements and considerations, and full MRE implementation. We also discuss how to choose the actuator type, size, and power based on the intended material and use. © 2022 Wiley Periodicals LLC. Basic Protocol 1: Design, construction, and implementation of a convertible pneumatic MRE actuator for use with tissues and phantom models Basic Protocol 2: Design, construction, and implementation of a piezoelectric MRE actuator for localized excitation in phantom models.

Indexed as

Elasticity Imaging TechniquesAnimalsBrainMagnetic Resonance ImagingMotionPhantoms, Imagingbiomechanicsmagnetic resonance elastographymagnetic resonance imagingMREMRI

Identifiers

PMID35286023
PMCPMC9517172

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.