Evidence map›Paper›PMID 35285946›Full record

ArticleCancer2022

Comparing adult-child and spousal caregiver burden and potential contributors.

Anny T H R Fenton, Nancy L Keating, Katherine A Ornstein, Erin E Kent, Kristin Litzelman, Julia H Rowland, Alexi A Wright

Open access · greenAbstract read
In one paragraph

Article in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
20.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
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  5. The influence of family resilience and benefit finding on the financial toxicity of primary caregivers of patients with advanced cancer: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  11. Psychometric validation of the Danish cancer caregiver roles and responsibilities scale.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Anny T H R FentonDivision of Population Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts.ORCID 0000-0002-0710-6719
Nancy L KeatingDepartment of Health Care Policy, Harvard Medical School, Boston, Massachusetts.
Katherine A OrnsteinDepartment of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Erin E KentDepartment of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina.ORCID 0000-0003-2503-2191
Kristin LitzelmanDepartment of Human Development and Family Studies, University of Wisconsin-Madison, Madison, Wisconsin.ORCID 0000-0002-5542-6434
Julia H RowlandSmith Center for Healing and the Arts, Washington, DC.
Alexi A WrightDivision of Population Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts.
Boston Medical Center · USBrigham and Women's Hospital · USDana-Farber Cancer Institute · USIcahn School of Medicine at Mount Sinai · USSmith Center for Healing and the Arts · USUniversity of North Carolina at Chapel Hill · USUniversity of Wisconsin–Madison · US

Funding

PROPENSITY SCORES IN HIERARCHICAL MODELSU01CA093344 · NCI · DANA-FARBER CANCER INSTITUTE · PI AYANIAN, JOHN Z., FOUAD, MONA N. · 2001 to 2011
$19.5M
Lung/Colon Cancer Outcomes--Cancer Research NetworkU01CA093332 · NCI · DANA-FARBER CANCER INSTITUTE · PI WEEKS, JANE C. · 2001 to 2008
$7.4M
RAND-UCLA CanCORS PDCR ApplicationU01CA093348 · NCI · RAND CORPORATION · PI KAHN, KATHERINE LESLIE · 2001 to 2008
$7.3M
Cancer Care Outcomes Research &Surveillance ConsortiumU01CA093324 · NCI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI AYANIAN, JOHN Z. · 2001 to 2008
$7.1M
RACIAL DISPARITIES IN END OF LIFE CARE--ACCESSU01CA093329 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FOUAD, MONA N. · 2001 to 2008
$6.6M
Lung Cancer Care Outcomes/Surveillance Consortium-IowaU01CA093339 · NCI · UNIVERSITY OF IOWA · PI WALLACE, ROBERT BRUCE · 2001 to 2008
$3.7M
Training in Oncology Population Sciences (TOPS)T32CA092203 · NCI · DANA-FARBER CANCER INST · PI Nancy L Keating, JENNIFER W MACK · 2018 to 2026
$3.7M
NCI NIH HHS T32 CA092203NCI NIH HHS U01 CA093324NCI NIH HHS U01 CA093329NCI NIH HHS U01 CA093332NCI NIH HHS U01 CA093339NCI NIH HHS U01 CA093344NCI NIH HHS U01 CA093348
6 · The paper itself

Abstract

backgroundAdult-children caring for a parent with cancer comprise a significant segment of caregivers. Yet less is known about adult-child caregivers, their burden, or caregivers' and patients' gender's impact, which may differ from the well-studied spousal caregiver. This knowledge gap may hinder efforts to ameliorate adult-children's caregiver burden.

methodsWe analyzed caregiver surveys from the Cancer Care Outcomes Research and Surveillance Consortium, a multi-regional population-based study of patients with colorectal or lung cancer. Using t tests and multivariate regression models, we assessed whether adult-child and spousal caregivers' caregiving responsibilities and social/emotional and financial burdens differed and used structural equation models (SEMs) to examine mediating factors.

resultsCompared with spouses/partners (N = 1007), adult-children (N = 227) spent less time caregiving (14 vs 23 hours/week; P < .001), but experienced higher social/ emotional burden (P < .01). In models adjusted for objective caregiving burden measures and demographics, adult-children's social/emotional (P < .05) and financial burdens (P < .01) were greater than spouses'. Poor communication quality was associated with greater social/emotional burden for both groups (P < .05). SEMs indicated that gender concordance between caregivers and patients (eg, daughters caring for mothers) and caregiver employment increased the difference between adult-child and spouses' social/emotional burden, whereas caregiver-patient relationship quality reduced it.

conclusionsAdult-children spend less time caregiving than spouses/partners, but have higher social/emotional and financial caregiving burdens, partially due to adult-children's employment, caregiver-patients' gender concordance, and relationship quality. Gender concordance's contribution to greater social/emotional burden adds important context to prior findings, indicating female caregivers experience the most burden. Interventions that improve caregiver-patient communication may reduce both adult-child and spousal caregiver burden.

Indexed as

Caregiver BurdenCost of IllnessAdultAdult ChildrenCaregiversFemaleHumansSpousescaregiver preparednesscaregiverscaregiving burdencommunicationfamiliesfinancial burden

Identifiers

PMID35285946
PMCPMC9038651
OpenAlexW4221126436

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.