← Statins × cardiovascular events

SynthesisJAMA internal medicine2022

Evaluating the Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment: A Systematic Review and Meta-analysis.

Paula Byrne et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedrandomised · 2022

Randomised comparison

Probably reduced cardiovascular events

−0.80percentage points−1.20 to −0.40

As reported

difference −0.80 %, 95% CI −1.20 to −0.40

Randomised comparison

Probably reduced cardiovascular events

−9.00percentage points−14.0 to −5.00

As reported

difference −9.00 %, 95% CI −14.0 to −5.00

Two numbers in the abstract

the abstract, start to end

… reductions in the absolute risk of 0.8% (95% CI, 0.4%-1.2%) for all-cause mortality, 1.3% (95% CI, 0.9%-1.7%) for myocardial infarction, and 0.4% (95% CI, 0.2%-0.6%) for stroke in those randomized to treatment with statins, with associated relative risk reductions of 9% (95% CI, 5%-14%), 29% (95% CI, …

← favours treatmentfavours comparator →
could be chance
Cardiovascular events
−0.80−1.20 to −0.40
Cardiovascular events
−9.00−14.0 to −5.00
StatinsCardiovascular events

Statins × cardiovascular eventshelps?replicated

unlikelylikely
0.86not counted
← favours treatmentfavours comparator →
more certainless certain
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