Evidence map›Paper›PMID 35285726›Full record

ArticleJournal of bacteriology2022

During Translesion Synthesis, Escherichia coli DinB89 (T120P) Alters Interactions of DinB (Pol IV) with Pol III Subunit Assemblies and SSB, but Not with the β Clamp.

Michelle K Scotland, Caleb Homiski, Mark D Sutton

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bacteriology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Direct visualization of translesion DNA synthesis polymerase IV at the replisome.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  2. Molecular insights into the prototypical single-stranded DNA-binding protein fromCritical reviews in biochemistry and molecular biology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michelle K ScotlandDepartment of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA.
Caleb HomiskiDepartment of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA.
Mark D SuttonDepartment of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York, USA.ORCID 0000-0002-8221-9297
University at Buffalo, State University of New York · US

Funding

Coordination of high fidelity replication with mutagenic translesion synthesisR01GM130761 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI GUARNE, ALBA, SUTTON, MARK D. · 2019 to 2022
$1.5M
NIGMS NIH HHS R01 GM130761
6 · The paper itself

Abstract

Translesion synthesis (TLS) by specialized DNA polymerases (Pols) is an evolutionarily conserved mechanism for tolerating replication-blocking DNA lesions. Using the Escherichia coli

Indexed as

Escherichia coliEscherichia coli ProteinsDNADNA-Binding ProteinsDNA-Directed DNA PolymeraseDNA Polymerase IIIDNA RepairDNA ReplicationDinB protein, E coliDNADNA-Binding ProteinsDNA-Directed DNA PolymeraseDNA Polymerase IIIEscherichia coli ProteinsSSB protein, E coliDinBDNA polymerase IIIDNA polymerase IVDNA replicationmutagenesispolymerase switchreplicasesingle-stranded DNA binding proteinsliding clamptranslation synthesis

Identifiers

PMID35285726
PMCPMC9017331
OpenAlexW4220886726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.