Evidence map›Paper›PMID 35285725›Full record

ArticleJournal of bacteriology2022

CsrA-Controlled Proteins Reveal New Dimensions of Acinetobacter baumannii Desiccation Tolerance.

Yasuhiro Oda, Madelyn M Shapiro, Nathan M Lewis, Xuefei Zhong, Holly K Huse, Weizhi Zhong, James E Bruce, Colin Manoil, Caroline S Harwood

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

  1. Loss of CsrA inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. New Insights intoPathogens (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Article
  6. Phenylacetic acid mediatesMicrobiology (Reading, England) · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Candidate transmission survival genome ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
  16. Review
  17. Review
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Yasuhiro OdaDepartment of Microbiology, University of Washingtongrid.34477.33, Seattle, Washington, USA.
Madelyn M ShapiroSeattle Children's Research Institute, Center for Global Infectious Disease Research, Seattle, Washington, USA.
Nathan M LewisDepartment of Plant and Microbial Biology, University of Minnesotagrid.17635.36, St. Paul, Minnesota, USA.
Xuefei ZhongAnalytical Chemistry Group, Regeneron Pharmaceuticals, Tarrytown, New York, USA.
Holly K HuseDepartment of Pathology, Harbor-UCLA Medical Center, Torrance, California, USA.
Weizhi ZhongDepartment of Microbiology, University of Washingtongrid.34477.33, Seattle, Washington, USA.
James E BruceDepartment of Genome Sciences, University of Washingtongrid.34477.33, Seattle, Washington, USA.
Colin ManoilDepartment of Genome Sciences, University of Washingtongrid.34477.33, Seattle, Washington, USA.
Caroline S HarwoodDepartment of Microbiology, University of Washingtongrid.34477.33, Seattle, Washington, USA.ORCID 0000-0003-4450-5177
University of Washington · USInfectious Disease Research Institute · USRegeneron (United States) · USUCLA Medical Center · USUniversity of Minnesota · US

Funding

Protein Interaction Technology CoreU19AI107775 · NIAID · UNIVERSITY OF WASHINGTON · PI MILLER, SAMUEL I · 2013 to 2017
$7.7M
NIAID NIH HHS U19 AI107775
6 · The paper itself

Abstract

Hospital environments are excellent reservoirs for the opportunistic pathogen Acinetobacter baumannii in part because it is exceptionally tolerant to desiccation. We found that relative to other A. baumannii strains, the virulent strain AB5075 was strikingly desiccation resistant at 2% relative humidity (RH), suggesting that it is a good model for studies of the functional basis of this trait. Consistent with results from other A. baumannii strains at 40% RH, we found the global posttranscriptional regulator CsrA to be critically important for desiccation tolerance of AB5075 at 2% RH. Proteomics experiments identified proteins that were differentially present in wild-type and

Indexed as

Acinetobacter baumanniiIntrinsically Disordered ProteinsAnimalsBiofilmsDesiccationHumansProteomicsIntrinsically Disordered ProteinsAcinetobacter baumanniiCsrAdesiccationintrinsically disordered proteins

Identifiers

PMID35285725
PMCPMC9017300
OpenAlexW4220790007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.