Evidence map›Paper›PMID 35285688›Full record

ArticleJournal of virology2022

Chondroitin Sulfate Proteoglycans Are De Facto Cellular Receptors for Human Papillomavirus 16 under High Serum Conditions.

Nathan R Fons, Rhonda C Kines, Cynthia D Thompson, Patricia M Day, Douglas R Lowy, John T Schiller

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nathan R FonsLaboratory of Cellular Oncology, National Cancer Institutegrid.48336.3a, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0001-7710-6274
Rhonda C KinesAura Biosciences, Cambridge, Massachusetts, USA.
Cynthia D ThompsonLaboratory of Cellular Oncology, National Cancer Institutegrid.48336.3a, National Institutes of Health, Bethesda, Maryland, USA.
Patricia M DayLaboratory of Cellular Oncology, National Cancer Institutegrid.48336.3a, National Institutes of Health, Bethesda, Maryland, USA.
Douglas R LowyLaboratory of Cellular Oncology, National Cancer Institutegrid.48336.3a, National Institutes of Health, Bethesda, Maryland, USA.
John T SchillerLaboratory of Cellular Oncology, National Cancer Institutegrid.48336.3a, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0001-7308-950X
National Institutes of Health · US

Funding

Understanding Papillomavirus Virion Proteins and VaccinesZIABC009052 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI SCHILLER, JOHN T. · 2009 to 2025
$38.4M
Papillomavirus Virion Proteins and VaccinesZIABC010579 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LOWY, DOUGLAS R. · 2009 to 2025
$15.4M
6 · The paper itself

Abstract

Human papillomaviruses (HPVs) are nonenveloped double-stranded DNA viruses that utilize heparan sulfate proteoglycans (HSPGs) as initial attachment factors prior to cell entry and infection. While extensively characterized, the selective interaction between HPV and HSPGs is generally studied using standard

Indexed as

Chondroitin Sulfate ProteoglycansHuman papillomavirus 16Papillomavirus InfectionsCell Line, TumorHeparan Sulfate ProteoglycansHumansProtein BindingSerum Albumin, BovineChondroitin Sulfate ProteoglycansHeparan Sulfate ProteoglycansSerum Albumin, Bovineglycosaminoglycanspapillomavirusvirus-host interactions

Identifiers

PMID35285688
PMCPMC9006963
OpenAlexW4220934078

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.