Evidence map›Paper›PMID 35285578›Full record

ArticleJournal of applied clinical medical physics2022

Biological effective dose in analysis of rectal dose in prostate cancer patients who underwent a combination therapy of VMAT and LDR with hydrogel spacer insertion.

Honglai Zhang, Lin Wang, Adam C Riegel, Jeffrey Antone, Louis Potters, Lucille Lee, Yijian Cao

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Honglai ZhangDepartment of Radiation Medicine, Northwell Health Cancer Institute, Lake Success, New York, USA.
Lin WangDepartment of Radiation Medicine, Northwell Health Cancer Institute, Lake Success, New York, USA.
Adam C RiegelDepartment of Radiation Medicine, Northwell Health Cancer Institute, Lake Success, New York, USA.
Jeffrey AntoneDepartment of Radiation Medicine, Northwell Health Cancer Institute, Lake Success, New York, USA.
Louis PottersDepartment of Radiation Medicine, Northwell Health Cancer Institute, Lake Success, New York, USA.
Lucille LeeDepartment of Radiation Medicine, Northwell Health Cancer Institute, Lake Success, New York, USA.
Yijian CaoDepartment of Radiation Medicine, Northwell Health Cancer Institute, Lake Success, New York, USA.
Northwell Health · USHofstra University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate rectal dose reduction in prostate cancer patients who underwent a combination of volumetric modulated arc therapy (VMAT) and low-dose-rate (LDR) brachytherapy with insertion of hydrogel spacer (SpaceOAR). For this study, 35 patients receiving hydrogel spacer and 30 patients receiving no spacer were retrospectively enrolled. Patient was treated to doses of 45 Gy to the primary tumor site and nodal regions over 25 fractions using VMAT and 100 Gy to the prostate using prostate seed implant (PSI). In VMAT plans of patients with no spacer, mean doses of rectal wall were 43.6, 42.4, 40.1, and 28.8 Gy to the volume of 0.5, 1, 2, and 5 cm

Indexed as

Prostatic NeoplasmsRadiotherapy, Intensity-ModulatedHumansHydrogelsMaleRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRectumRetrospective StudiesHydrogelsbiological effective dose (BED)hydrogel spacerLDR brachytherapyprostate cancerVMAT and PSI

Identifiers

PMID35285578
PMCPMC9194986
OpenAlexW4221009650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.