Evidence map›Paper›PMID 35285514›Full record

ArticleCardiology journal2024

Long-term outcomes and quality of life following implementation of dedicated mitral valve Heart Team decisions for patients with severe mitral valve regurgitation in tertiary cardiovascular care center.

Szymon Jonik, Michał Marchel, Ewa Pędzich-Placha, Arkadiusz Pietrasik, Adam Rdzanek, Zenon Huczek, Janusz Kochman, Monika Budnik, Radosław Piątkowski, Piotr Scisło and 8 more

Open access · goldAbstract read
In one paragraph

Article in Cardiology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Szymon Jonik1st Department of Cardiology, Medical University of Warsaw, Poland.ORCID 0000-0002-9230-5455
Michał Marchel1st Department of Cardiology, Medical University of Warsaw, Poland.
Ewa Pędzich-Placha1st Department of Cardiology, Medical University of Warsaw, Poland.
Arkadiusz Pietrasik1st Department of Cardiology, Medical University of Warsaw, Poland.
Adam Rdzanek1st Department of Cardiology, Medical University of Warsaw, Poland.
Zenon Huczek1st Department of Cardiology, Medical University of Warsaw, Poland.
Janusz Kochman1st Department of Cardiology, Medical University of Warsaw, Poland.
Monika Budnik1st Department of Cardiology, Medical University of Warsaw, Poland.
Radosław Piątkowski1st Department of Cardiology, Medical University of Warsaw, Poland.
Piotr Scisło1st Department of Cardiology, Medical University of Warsaw, Poland.
Janusz Kochanowski1st Department of Cardiology, Medical University of Warsaw, Poland.
Paweł CzubDepartment of Cardiac Surgery, Medical University of Warsaw, Poland.
Radosław WilimskiDepartment of Cardiac Surgery, Medical University of Warsaw, Poland.
Piotr HendzelDepartment of Cardiac Surgery, Medical University of Warsaw, Poland.
Marcin Grabowski1st Department of Cardiology, Medical University of Warsaw, Poland.
Krzysztof J Filipiak1st Department of Cardiology, Medical University of Warsaw, Poland.
Grzegorz Opolski1st Department of Cardiology, Medical University of Warsaw, Poland.
Tomasz Mazurek1st Department of Cardiology, Medical University of Warsaw, Poland. tomaszmazurek.wum@gmail.com.ORCID 0000-0002-3693-8741
Medical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study was purposed to investigate which treatment strategy was associated with the most favourable prognosis for patients with severe mitral regurgitation (MR) following Heart Team (HT)-decisions implementation.

methodsIn this retrospective study, long-term outcomes of patients with severe MR qualified after HT discussion to: optimal medical treatment (OMT) alone, OMT and MitraClip (MC) procedure or OMT and mitral valve replacement (MVR) were evaluated. The primary endpoint was defined as cardiovascular (CV) death and the secondary endpoints included all-cause mortality, myocardial infarctions (MI), strokes, hospitalizations for heart failure exacerbation and CV events during a mean (standard deviation [SD]) follow-up of 29 (15) months.

resultsFrom 2016 to 2019, 176 HT meetings were held and a total of 157 participants (mean age [SD] = 71.0 [9.2], 63.7% male) with severe MR and completely implemented HT decisions (OMT, MC or MVR for 53, 58 and 46 patients, respectively) were included into final analysis. Comparing OMT, MC and MVR groups statistically significant differences between the implemented procedures and occurrence of primary and secondary endpoints with the most frequent in OMT-group were observed (p < 0.05). However, for interventional strategy MC was non-inferior to MVR for all endpoints (p > 0.05). General health status assessed at the end of follow-up were significantly the lowest for MVR, then for MC and the highest for OMT-group (p < 0.01).

conclusionsIn the present study it was demonstrated that after careful HT evaluation of patients with severe MR at high risk of surgery, percutaneous strategy (MC) can be considered as equivalent to surgical treatment (MVR) with non-inferior outcomes.

Indexed as

Heart Valve Prosthesis ImplantationMitral Valve InsufficiencyFemaleHumansMaleMitral ValveQuality of LifeRetrospective StudiesTreatment Outcomeheart failureHeart TeamMitraClipmitral regurgitationmitral valve replacement

Identifiers

PMID35285514
PMCPMC10919556
OpenAlexW4220914173

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.