Evidence map›Paper›PMID 35285281›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2022

Single-cell RNA-seq identification of four differentially expressed survival-related genes by a TARGET: Osteosarcoma database analysis.

Mesalie Feleke, Wenyu Feng, Emel Rothzerg, Dezhi Song, Qingjun Wei, Sulev Kõks, David Wood, Yun Liu, Jiake Xu

Open access · bronzeAbstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Mesalie FelekeSchool of Biomedical Sciences, The University of Western Australia, Perth, WA 6009, Australia.
Wenyu FengDepartment of Orthopaedics, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Emel RothzergSchool of Biomedical Sciences, The University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0003-1957-930X
Dezhi SongSchool of Biomedical Sciences, The University of Western Australia, Perth, WA 6009, Australia.
Qingjun WeiDepartment of Orthopaedics, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Sulev KõksPerron Institute for Neurological and Translational Science, Queen Elizabeth II Medical Centre, Nedlands, WA 6009, Australia.ORCID 0000-0001-6087-6643
David WoodMedical School, The University of Western Australia, Perth, WA 6009, Australia.
Yun LiuSchool of Biomedical Sciences, The University of Western Australia, Perth, WA 6009, Australia.
Jiake XuSchool of Biomedical Sciences, The University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0003-2021-8309
Guangxi Medical University · CNThe University of Western Australia · AUMurdoch University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma (OS) differentially expressed genes (DEGs) have been predicted using the data portal of the Therapeutically Applicable Research to Generate Effective Treatments (TARGET). In this study, we sought to identify cell types that specially express key DEGs (

Indexed as

Bone NeoplasmsOsteosarcomaEndothelial CellsGene Expression ProfilingGene Expression Regulation, NeoplasticHumansRNA-Seqdifferentially expressed genesheterogeneityOsteosarcomasarcomasingle-cell sequencingTARGET

Identifiers

PMID35285281
PMCPMC9189571
OpenAlexW4221029983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.