Evidence map›Paper›PMID 35285273›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

Clinicopathological Findings Associated With Cervical Lymph Node Metastasis in Papillary Thyroid Microcarcinoma: A Retrospective Study in China.

Yimeng Shi, Zheyu Yang, Yu Heng, Huijun Ju, Yu Pan, Yifan Zhang

Open access · goldAbstract read
In one paragraph

Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  11. Integrating US-guided FNAB, BRAFEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
  12. [Progress in active surveillance for adult low-risk papillary thyroid microcarcinoma].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023
    Article
  13. Younger Than 55 Years Old andInternational journal of general medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yimeng ShiDepartment of Nuclear Medicine, Ruijin Hospital, 66281Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zheyu YangDepartment of General Surgery, Ruijin Hospital, 66281Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yu HengDepartment of Otolaryngology, Eye Ear Nose and Throat Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-5625-8324
Huijun JuDepartment of Nuclear Medicine, Ruijin Hospital, 66281Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yu PanDepartment of Nuclear Medicine, Ruijin Hospital, 66281Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yifan ZhangDepartment of Nuclear Medicine, Ruijin Hospital, 66281Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0001-6488-6232
Shanghai Jiao Tong University · CNEye & ENT Hospital of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe incidence of papillary thyroid microcarcinoma (PTMC) has increased sharply during the past decades. Yet, whether or not nodal dissection should be performed remains controversial. This article aims to assess the high-risk factors associated with cervical lymph node metastasis (LNM) in patients with PTMC, which may potentially guide clinical management decision-making.

methodsMedical records of 449 PTMC patients who underwent thyroidectomy in our hospital from August 2016 to July 2017 were retrospectively reviewed. Clinical and pathological factors of the patients were anonymously extracted from the charts and analyzed.

resultThe patients were classified into two subgroups according to maximum tumor size measured through post-surgical pathology: smaller PTMC group (≤5 mm) and larger PTMC group (>5 mm). Larger tumor size was found to be associated with a higher rate of LNM (

conclusionsFor the PTMC population, tumor size was an independent risk factor for LNM, particularly for patients of old age (>55 y), and multifocality. However, in PTMC patients with unilateral lesions without extrathyroidal extension, tumor size was not related to the risk of LNM. These findings may potentially guide clinical decision-making in terms of cervical nodal dissection.

Indexed as

Carcinoma, PapillaryAgedChinaHumansLymphatic MetastasisRetrospective StudiesThyroid Neoplasmslymph node metastasispapillary thyroid microcarcinomastagingtumor sizeunilateral lesions

Identifiers

PMID35285273
PMCPMC8922184
OpenAlexW4220657938

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.