ArticleAlcohol and alcoholism (Oxford, Oxfordshire)2022
A Scoping Review of Gender, Sex and Sexuality Differences in Polysubstance Use in Adolescents and Adults.
Article in Alcohol and alcoholism (Oxford, Oxfordshire), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 49 citations in OpenAlex.
- Implementation of contingency management with women engaging in polysubstance use.Addiction science & clinical practice · 2025Trial
- Targeted Oral Naltrexone for Mild to Moderate Alcohol Use Disorder Among Sexual and Gender Minority Men: A Randomized Trial.The American journal of psychiatry · 2022Trial
- Substance use patterns from late childhood to mid-adolescence: Updates on the Adolescent Brain Cognitive Development Study.Drug and alcohol dependence reports · 2026Article
- Psychological, behavioral, cognitive and social factors associated with single vs dual alcohol and cannabis use in adolescents with chronic pain.Addictive behaviors · 2026Article
- Cannabis and Tobacco Product Use Classes and Psychosocial Correlates Among US Young Adults.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026Article
- Broad-Spectrum Drug Screening Positivity Rates in Pediatrics and Adults: The Reference Laboratory Perspective.Therapeutic drug monitoring · 2026Article
- The role of polysubstance use in the development, maintenance, and treatment of stimulant use disorders.Pharmacological reviews · 2026Review
- Disproportionate use of polysubstance combinations varies by sexual identity among US adults.PloS one · 2026Article
- Monthly simultaneous cannabis and alcohol use: effects on depression, anxiety, and stress in male and female college students.Journal of cannabis research · 2025Article
- Risk for Adolescent Substance Use Initiation: Associations with Large-Scale Brain Network Recruitment During Emotional Inhibitory Control.Behavioral sciences (Basel, Switzerland) · 2025Article
- Daily patterns of single and poly-substance use among adolescent and young adult females: A day-level latent class analysis.Addictive behaviors · 2025Article
- Sex differences in the impact of social determinants of health on substance use disorder treatment outcomes.Biology of sex differences · 2025Article
- Leveraging pooled medical examiner records to surveil complex and emerging patterns of polysubstance use in the United States.The International journal on drug policy · 2025Article
- Male Predominance in West Virginia Unintentional Overdose Deaths Is Influenced by Alcohol and Co-Intoxicants.Journal of studies on alcohol and drugs · 2025Article
- Temporal stability and volatility in population-level high-risk illicit polysubstance use by gender and marital status in the United States, 2002-2019.Social science & medicine (1982) · 2025Article
- Syndemic conditions associated with hazardous alcohol consumption among sexual minority men in San Francisco.Drug and alcohol dependence reports · 2024Article
- Tobacco, cannabis, alcohol, and polysubstance use disparities among sexual identity groups of US young adult women and men.Addictive behaviors reports · 2024Article
- Higher prevalence of polysubstance use among older lesbian, and gay US adults.Drug and alcohol dependence reports · 2024Article
- Substance use patterns, quantities, and associated risk factors in women with polysubstance misuse.Addiction biology · 2024Observational
- Experiences of and recommendations for LGBTQ+-affirming substance use services: an exploratory qualitative descriptive study with LGBTQ+ people who use opioids and other drugs.Substance abuse treatment, prevention, and policy · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundPolysubstance use is a common, problematic behavior that increases risk of harm to self and others. Research suggests that rates may vary based on gender, sex and sexuality. Understanding the current state of this literature may inform prevention and treatment of polysubstance use, leading to reduced public health burden.
objectivesThis review aimed to synthesize research on gender, sex and sexuality differences in polysubstance use in adults and adolescents.
methodsA scoping review was conducted using all EBSCO databases, PubMed and Google Scholar to identify articles examining the effects of gender, sex and sexuality on polysubstance use. Polysubstance use was defined broadly as the use of any combination of substances over any time period and included licit (alcohol, tobacco) and illicit substances, concurrent and simultaneous use, from lifetime to daily use and use at any frequency. Studies were considered if they were published in peer-reviewed journals between January 1990 and October 2020 and were written in English. Publicly available data sources were also utilized to fully capture prevalence data that has not been published elsewhere.
resultsFindings were mostly inconsistent and often conflicting. Only two findings were generally consistent: adult men were overall more likely to report polysubstance use than adult women, and sexual and gender minorities report more frequent polysubstance use than non-minorities.
conclusionsResearch has been unable to clearly elucidate differences in polysubstance use prevalence and patterns according to gender, sex and sexuality. Several recommendations are offered to advance future research and address limitations of current research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.