ArticleSTAR protocols2022
Using intra-brain drug infusion to investigate neural mechanisms underlying reward-seeking behavior in mice.
Article in STAR protocols, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed.
- Monitoring in real time and far-red imaging of HNature chemical biology · 2026Article
- The prelimbic prefrontal cortex mediates the development of lasting social avoidance as a consequence of social threat conditioning.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- 3D nanoprinting of embryo microinjection needles with anti-clogging features.Microsystems & nanoengineering · 2025Article
- Maternal behavior promotes resilience to adolescent stress in mice through a microglia-neuron axis.Nature communications · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain-region-specific drug infusion is a key way to investigate neural mechanisms underlying behavior and neurological diseases. Here, we present a detailed protocol for cannula implantation, intra-brain drug infusion, and two reward-seeking-related behavioral paradigms in mice: the light/dark box test and touchscreen version of progressive ratio test. In addition, we provide a user-friendly Python-based tool for behavioral data analysis. This protocol can be easily adapted to address various research questions related to behavioral pharmacology. For complete details on the use and execution of this protocol, please refer to Peng et al. (2021).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.