Evidence map›Paper›PMID 35284630›Full record

ArticleMolecular therapy oncolytics2022

Hsa_circ_0001666 promotes non-small cell lung cancer migration and invasion through miR-1184/miR-548I/AGO1 axis.

Xueting Wang, Rui Li, Lingxin Feng, Jing Wang, Qi Qi, Wenjie Wei, Zhuang Yu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy oncolytics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
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  4. Article
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  7. Article
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  11. Article
  12. The roles and mechanisms of circular RNAs related to mTOR in cancers.Journal of clinical laboratory analysis · 2022
    Review
  13. Review
  14. Circular RNAs Involved in the Regulation of the Age-Related Pathways.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xueting WangDepartment of Oncology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266000, China.
Rui LiHealth Management Center, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266000, China.
Lingxin FengDepartment of Oncology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266000, China.
Jing WangDepartment of Oncology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266000, China.
Qi QiDepartment of Oncology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266000, China.
Wenjie WeiDepartment of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Zhuang YuDepartment of Oncology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266000, China.
Qingdao University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence has revealed that the dysregulation of circular RNAs (circRNAs) plays crucial roles in the occurrence and progression of cancers. However, the aberrant expression profile and dysfunction of circRNAs in non-small cell lung cancer (NSCLC) have not been fully explored. Herein, we discovered that a circRNA, hsa_circ_0001666 (circ0001666), was highly expressed in NSCLC tissues and cell lines, and it was positively correlated with NSCLC tumor pathological grade and lymph node metastasis. Moreover, Kaplan-Meier survival analysis implied that NSCLC patients with high circ0001666 expression were negatively correlated with favorable survival. Functionally, circ0001666 could promote migration and invasion of NSCLC cells

Indexed as

AGO1circ0001666miR-1184miR-548Inon-small cell lung cancerPI3K/AKT/mTOR

Identifiers

PMID35284630
PMCPMC8892028
OpenAlexW4212793084

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.