Evidence map›Paper›PMID 35284496›Full record

ArticleFrontiers in cardiovascular medicine2021

Diabetes Is Associated With Rapid Progression of Aortic Stenosis: A Single-Center Retrospective Cohort Study.

Kangning Han, Dongmei Shi, Lixia Yang, Meng Xie, Rongrong Zhong, Zhijian Wang, Fei Gao, Xiaoteng Ma, Yujie Zhou

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Aortic valve replacement in uncontrolled diabetes: a matter of causes - effect.International journal of cardiology. Heart & vasculature · 2025
    Article
  8. Article
  9. Article
  10. Article
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  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Kangning HanBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Dongmei ShiBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Lixia YangBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Meng XieDepartment of Echocardiogram, Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Rongrong ZhongFaculty of Medicine, Imperial College London, London, United Kingdom.
Zhijian WangBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Fei GaoBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Xiaoteng MaBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yujie ZhouBeijing Anzhen Hospital, Capital Medical University, Beijing, China.
Beijing Institute of Water · CNMinistry of Education of the People's Republic of China · CNBeijing Anzhen Hospital · CNCapital Medical University · CNImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mounting evidence indicates that rapid progression of aortic stenosis (AS) is significantly associated with poor prognosis. Whether diabetes accelerates the progression of AS remains controversial. Objectives: The purpose of the present study was to investigate whether diabetes was associated with rapid progression of AS. Methods: We retrospectively analyzed 276 AS patients who underwent transthoracic echocardiography at least twice with a maximum interval ≥ 180 days from January 2016 to June 2021. AS severity was defined by specific threshold values for peak aortic jet velocity (V Results: At a median echocardiographic follow-up interval of 614 days, the annual increase of V Conclusions: Diabetes was strongly and independently associated with rapid progression of AS.

Indexed as

aortic stenosisdiabetesrapid progressiontransthoracic echocardiographyvalvular disease

Identifiers

PMID35284496
PMCPMC8904744
OpenAlexW4214712214

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.