Evidence map›Paper›PMID 35284255›Full record

ArticleQuantitative imaging in medicine and surgery2022

Pharmaco-mechanical catheter-directed thrombolysis versus recanalization and stenting for post thrombotic syndrome after lower limb deep vein thrombosis: a comparative study.

Giovanni Gautier, Frederic Douane, Arthur David, Christophe Perret, Marc-Antoine Pistorius, Yann Goueffic, Jerôme Connault, Mathieu Artifoni, Cecile Durant, Gaëtan Ploton and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Giovanni GautierDepartment of Internal and Vascular Medicine, CHU de Nantes, Nantes, France.
Frederic DouaneDepartment of Radiology, CHU de Nantes, Nantes, France.
Arthur DavidDepartment of Radiology, CHU de Nantes, Nantes, France.
Christophe PerretDepartment of Radiology, CHU de Nantes, Nantes, France.
Marc-Antoine PistoriusDepartment of Internal and Vascular Medicine, CHU de Nantes, Nantes, France.
Yann GouefficDepartment of Vascular and Endovascular Surgery, Groupe Hospitalier St. Joseph, Paris, France.
Jerôme ConnaultDepartment of Internal and Vascular Medicine, CHU de Nantes, Nantes, France.
Mathieu ArtifoniDepartment of Internal and Vascular Medicine, CHU de Nantes, Nantes, France.
Cecile DurantDepartment of Internal and Vascular Medicine, CHU de Nantes, Nantes, France.
Gaëtan PlotonDepartment of Internal and Vascular Medicine, CHU de Nantes, Nantes, France.
Alizee RaimbeauDepartment of Internal and Vascular Medicine, CHU de Nantes, Nantes, France.
Guillaume BergereDepartment of Internal and Vascular Medicine, CHU de Nantes, Nantes, France.
Olivier RobinDepartment of Internal and Vascular Medicine, CHU de Nantes, Nantes, France.
Blandine MaurelDepartment of Vascular Surgery, CHU de Nantes, Nantes, France.
Olivier EspitiaDepartment of Internal and Vascular Medicine, CHU de Nantes, Nantes, France.
Centre Hospitalier Universitaire de Nantes · FRNantes Université · FRHôpital Paris Saint-Joseph · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Endovenous interventional procedures can be used in addition to therapeutic anticoagulation to treat deep vein thrombosis in selected patients with proximal vein involvement (vena cava, iliac and/or common femoral). The aim of this study was to compare venous patency and the post-thrombotic syndrome (PTS) in patients treated with pharmaco-mechanical catheter-directed thrombolysis (PMT) versus recanalization-stenting for PTS after a proximal lower limb deep vein thrombosis. Methods: Between January 2014 and December 2020, this retrospective and monocentric study included patients with very symptomatic acute iliofemoral deep vein thrombosis treated with PMT within 21 days after diagnosis (PMT group) and patients with PTS caused by chronic venous obstruction treated with recanalization and stenting (CRS group). Results: A total of 116 patients were included (26 PMT, 90 CRS). The rate of primary patency was 81.8% (18/22 patients) in the PMT group and 78.4% (69/88) in the CRS group (P>0.99). The rate of venous patency at the last follow-up was 76.9% (20/26) in the PMT group and 82.2% (74/90) in the CRS group (P=0.57). The median number of stents was 2 (range, 0-5) in the PMT group and 3 (range, 0-7) in the CRS group (P<0.001). The median stent length was 150 mm (range, 60-390 mm) and 280 mm (range, 120-820 mm), respectively (P<0.001). The median last Villalta score was 2 (range, 0-10) in the PMT group and 2 (range, 0-21) in the CRS group (P=0.55). The rate of venous claudication at the last follow-up was 19.0% (4/21) in the PMT group and 12.0% (10/83) in the CRS group (P=0.47). Conclusions: In this study, there was no difference in venous patency and in the rate and severity of PTS between the PMT and CRS groups. The number of stent and their length were significantly lower in the PMT group compared with the CRS group.

Indexed as

Deep vein thrombosis (DVT)pharmaco-mechanical catheter-directed thrombolysis (PMT)post-thrombotic syndrome (PTS)venous angioplasty and stentingVillalta score

Identifiers

PMID35284255
PMCPMC8899969
OpenAlexW4205246346

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.