Evidence map›Paper›PMID 35284126›Full record

ArticleJournal of gastrointestinal oncology2022

The predictive value of routine laboratory tests for colorectal polyps: a retrospective study.

Xinyi Feng, Xiuping Jiao, Yemin Xu, Xi Xu, Yan Zhu, Qiang She, Yaoyao Li, Guiqing Li, Jian Wu, Weiming Xiao and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of gastrointestinal oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Xinyi Feng *Department of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou, China.
Xiuping Jiao *Department of Health Management Centre, Affiliated Hospital of Yangzhou University, Yangzhou, China.
Yemin XuDepartment of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou, China.
Xi XuDepartment of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou, China.
Yan ZhuSchool of Medicine of Yangzhou University, Yangzhou, China.
Qiang SheDepartment of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou, China.
Yaoyao LiDepartment of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou, China.
Guiqing LiDepartment of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou, China.
Jian WuDepartment of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou, China.
Weiming XiaoDepartment of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou, China.
Yanbing DingDepartment of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou, China.
Bin DengDepartment of Gastroenterology, Affiliated Hospital of Yangzhou University, Yangzhou, China.
Yangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Colorectal cancer (CRC) has become the malignant tumor of the digestive tract with the highest incidence in our country, posing a serious threat to the health of our people. Early colon cancer is mostly due to the malignant transformation of colon polyps, so that early detection and resection have been shown to be effective in reducing the incidence and mortality of CRC. This study tried to investigate the related risk factors of and construct a predictive nomogram for colorectal polyps, providing meaningful guidance basis for risk stratification and screening. Methods: A total of 1,799 patients who underwent colonoscopies in the Health Management Centre of the Affiliated Hospital of Yangzhou University were recruited to this study. Univariate and multivariate logistic analyses were performed to determine the risk factors for colorectal polyps, and a predictive nomogram was constructed based on the multivariable model. We determined the predictive value of the nomogram by receiver operating characteristic (ROC) curve, calibration curve, and decision curve analyses (DCAs). Results: The logistic regression analysis showed that age (P<0.001), gender (P<0.001), eosinophil count (P=0.005), hemoglobin level (P=0.039), and LDL-C/HDL-C ratio (LHR; P<0.001) were independent predictors of the development of colorectal polyps. The above independent risk factors were incorporated, and an individualized nomogram model was successfully established. The C-index of the nomogram was 0.679 in our model, and with the bootstrap method, the prediction curve fit well with the ideal curve, suggesting that the prediction curve constructed in this study has good predictive ability. Conclusions: Age, gender, eosinophil count, hemoglobin level, and LHR are risk factors for the development of colorectal polyps. Establishing a nomogram prediction model for colorectal polyps is helpful for the early clinical screening of high-risk patients with colorectal polyps, improving the detection rate of polyps and reducing the incidence of colorectal cancer (CRC).

Indexed as

Colorectal polypsnomogrampredictive modelrisk factors

Identifiers

PMID35284126
PMCPMC8899762
OpenAlexW4212861985

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.