ArticleSouthern African journal of HIV medicine2022
Predictors of low antiretroviral adherence at an urban South African clinic: A mixed-methods study.
Article in Southern African journal of HIV medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Prevalence and predictors of virological failure among the people living with HIV on antiretroviral treatment in East Africa: evidence from a systematic review with meta-analysis and meta-regression of published studies from 2016 to 2023.HIV research & clinical practice · 2025Pooled it
- The Impact of a Household Intervention on ART Adherence and Household HIV Competency for People Living with HIV: Results from a Cluster-Randomised Controlled Trial in Cape Town, South Africa.AIDS and behavior · 2026Article
- Longitudinal adherence trajectories measured by electronic dose monitoring and viral non-suppression in a South African HIV cohort study.BMC infectious diseases · 2026Article
- Barriers to Antiretroviral Therapy Adherence Among Children in Ekurhuleni, South Africa: A Descriptive Study.International journal of environmental research and public health · 2026Article
- Prevalence and Factors Associated with Non-Adherence To Anti-retroviral Therapy among People Living with HIV.Journal of community health · 2026Article
- Burden and predictors of advanced HIV disease among people living with HIV at Zewditu Memorial Hospital in Addis Ababa, Ethiopia.Frontiers in public health · 2026Article
- Demographic and Socioeconomic Factors Associated With ART Nonadherence Among 15 Years and Older South Africans. Evidence From the 2022 Cross-Sectional Population-Based Household Survey.AIDS research and treatment · 2026Article
- Perceptions of adolescents and young adults failing antiretroviral therapy on adherence in Gauteng, South Africa.Southern African journal of HIV medicine · 2026Article
- Persistence to Adjuvant Endocrine Therapy for Breast Cancer in Botswana: An Observational Cohort Analysis.Breast care (Basel, Switzerland) · 2025Article
- Determinants of Non-Adherence to Anti-Tuberculosis Treatment in a Public Primary Healthcare Clinic in South Africa: Improving the Quality of Long-Term Care.International journal of environmental research and public health · 2025Article
- Beliefs of Pentecostal pastors on the use of antiretroviral treatment among Pentecostal Christians living with HIV in a suburb of Cape Town-South Africa: a community health systems lens.Health policy and planning · 2025Article
- Factors Associated with Non-Adherence to Antiretroviral Therapy: A Health-Facility-Based Cross-Sectional Study in the Amahlathi Sub-District of the Eastern Cape, South Africa.HIV/AIDS (Auckland, N.Z.) · 2025Article
- Prevalence and Associated Factors of Treatment Regimen Fatigue Among People Living with HIV/AIDS in China: A Cross-Sectional Survey.Patient preference and adherence · 2025Article
- Programmatic outcomes of adolescents in differentiated service delivery models in South Africa.Southern African journal of infectious diseases · 2025Article
- HIV treatment default in sub-Saharan Africa: issues and possible solutions.Frontiers in medicine · 2025Article
- Pathways to Poor Adherence to Antiretroviral Therapy Among People Living with HIV: The Role of Food Insecurity and Alcohol Misuse.AIDS and behavior · 2024Article
- Primary health care providers' views on managing substance use among people living with HIV.African journal of primary health care & family medicine · 2023Article
- Relationship between People's Interest in Medication Adherence, Health Literacy, and Self-Care: An Infodemiological Analysis in the Pre- and Post-COVID-19 Era.Journal of personalized medicine · 2023Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Low adherence to antiretroviral treatment (ART) in people living with HIV (PLHIV) remains a critical issue, especially in vulnerable populations. Although ART is responsible for greatly reducing the mortality and morbidity associated with HIV, low treatment adherence continues to impact the effectiveness of ART. Considering that a high level of adherence to ART is required for the excellent clinical outcomes with which ART is often associated, understanding the complex contextual and personal factors that limit high levels of treatment adherence remains paramount. Poor adherence remains an issue in many South African communities many years after the introduction of ART. Objectives: Our study sought to understand the specific factors and the interactions among them that contribute to non-adherence in this patient population in order to devise successful and contextually appropriate interventions to support ART adherence in PLHIV. Methods: This mixed-methods study employed a study-specific questionnaire ( Results: Over half (57.3%) of participants were ART non-adherent. Non-adherence was correlated with younger age, negative self-image and a low belief in the necessity of ART ( Conclusion: The results suggest that there remains a need for context-sensitive interventions to support PLHIV in South African communities. Future research needs to ensure that these targeted interventions take these factors into consideration.
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Registered trials
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