Evidence map›Paper›PMID 35284002›Full record

ArticleCardiovascular therapeutics2022

Methylenetetrahydrofolate Reductase Gene rs1801133 and rs1801131 Polymorphisms and Essential Hypertension Risk: A Comprehensive Analysis.

Yingchao Fan, Liting Wu, Wenfang Zhuang

Open access · goldAbstract read
In one paragraph

Article in Cardiovascular therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  7. Impact ofReports of biochemistry & molecular biology · 2024
    Article
  8. Genetic variants and mRNA expression levels ofJournal of biomedical research · 2024
    Article
  9. Susceptibility to hypertension based onFrontiers in cardiovascular medicine · 2023
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yingchao FanMedical Laboratory, Shidong Hospital Affiliated to University of Shanghai for Science and Technology, No. 999, Shiguang Road, 200438 Yangpu District, Shanghai, China.
Liting WuMedical Laboratory, Shidong Hospital Affiliated to University of Shanghai for Science and Technology, No. 999, Shiguang Road, 200438 Yangpu District, Shanghai, China.
Wenfang ZhuangMedical Laboratory, Shidong Hospital Affiliated to University of Shanghai for Science and Technology, No. 999, Shiguang Road, 200438 Yangpu District, Shanghai, China.ORCID https://orcid.org/0000-0002-2877-9349
University of Shanghai for Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Essential hypertension (EH) is a common and multifactorial disorder that is likely to be influenced by multiple genes. The methylenetetrahydrofolate reductase ( Results: Overall, 10712 patients and 11916 controls were involved; we observed significantly increased association between the Conclusions: Our study provides evidence that the

Indexed as

Genetic Predisposition to DiseaseMethylenetetrahydrofolate Reductase (NADPH2)Asian PeopleEssential HypertensionHumansPolymorphism, Single NucleotideMethylenetetrahydrofolate Reductase (NADPH2)

Identifiers

PMID35284002
PMCPMC8888071
OpenAlexW4214510316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.