Evidence map›Paper›PMID 35283783›Full record

ReviewFrontiers in physiology2022

Spinal Reflex Control of Arterial Blood Pressure: The Role of TRP Channels and Their Endogenous Eicosanoid Modulators.

Zeljka Minic, Donal S O'Leary, Christian A Reynolds

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Neuroprosthetic closed-loop strategy for sustained blood pressure reduction via simultaneous stimulation and recording from the spinal cord.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
  3. Article
  4. Review
  5. Review
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Zeljka MinicDepartment of Emergency Medicine Wayne State University School of Medicine, Detroit, MI, United States.
Donal S O'LearyDepartment of Physiology, Wayne State University School of Medicine, Detroit, MI, United States.
Christian A ReynoldsDepartment of Emergency Medicine Wayne State University School of Medicine, Detroit, MI, United States.
University of Rijeka · HRWayne State University · US

Funding

BLOOD PRESSURE CONTROL DURING EXERCISE IN HEART FAILURER01HL055473 · NHLBI · WAYNE STATE UNIVERSITY · PI O'LEARY, DONAL S · 1996 to 2024
$9.8M
Regulation of Viscerosensory Sympathetic Reflexes: The Role of Diet-Derived Lipid Mediators.R01DK121812 · NIDDK · WAYNE STATE UNIVERSITY · PI O'LEARY, DONAL S · 2020 to 2024
$2.2M
NHLBI NIH HHS R01 HL055473NIDDK NIH HHS R01 DK121812
6 · The paper itself

Abstract

The spinal cord is an important integrative center for blood pressure control. Spinal sensory fibers send projections to sympathetic preganglionic neurons of the thoracic spinal cord and drive sympathetically-mediated increases in blood pressure. While these reflexes responses occur in able-bodied individuals, they are exaggerated following interruption of descending control - such as occurs following spinal cord injury. Similar reflex control of blood pressure may exist in disease states, other than spinal cord injury, where there is altered input to sympathetic preganglionic neurons. This review primarily focuses on mechanisms wherein visceral afferent information traveling

Indexed as

blood pressure (BP)eicosanoids in physiological and pathological processesspinal cord injurysympathetic nerve activity (SNA)transient receptor potential (TRP) channelvisceral reflexes

Identifiers

PMID35283783
PMCPMC8904930
OpenAlexW4214618873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.