Evidence map›Paper›PMID 35283750›Full record

ArticleFrontiers in aging neuroscience2022

Behavioral and Cellular Tagging in Young and in Early Cognitive Aging.

Alexandra Gros, Amos W H Lim, Victoria Hohendorf, Nicole White, Michael Eckert, Thomas John McHugh, Szu-Han Wang

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Standardized extract ofLearning & memory (Cold Spring Harbor, N.Y.) · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexandra GrosCentre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, United Kingdom.
Amos W H LimCentre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, United Kingdom.
Victoria HohendorfCentre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, United Kingdom.
Nicole WhiteCentre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, United Kingdom.
Michael EckertCanadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, AB, Canada.
Thomas John McHughLaboratory for Circuit and Behavioral Physiology, RIKEN Center for Brain Science, Saitama, Japan.
Szu-Han WangCentre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to maintain relevant information on a daily basis is negatively impacted by aging. However, the neuronal mechanism manifesting memory persistence in young animals and memory decline in early aging is not fully understood. A novel event, when introduced around encoding of an everyday memory task, can facilitate memory persistence in young age but not in early aging. Here, we investigated in male rats how sub-regions of the hippocampus are involved in memory representation in behavioral tagging and how early aging affects such representation by combining behavioral training in appetitive delayed-matching-to-place tasks with the "cellular compartment analysis of temporal activity by fluorescence

Indexed as

behavioral taggingcognitive agingimmediate early genesin situ hybridizationmemory consolidationproximal and distal hippocampustrisynaptic circuit

Identifiers

PMID35283750
PMCPMC8907879

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.