ArticleClinical, cosmetic and investigational dermatology2022
Post-Traumatic Stress in Vitiligo Patients: A Neglected but Real-Existing Psychological Impairment.
Article in Clinical, cosmetic and investigational dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- A 5-week low-dose prednisolone regimen for progressive vitiligo: efficacy and safety in a single-center cohort study.Annals of medicine · 2025Article
- Leflunomide-Mediated Immunomodulation Inhibits Lesion Progression in a Vitiligo Mouse Model.International journal of molecular sciences · 2025Article
- Post-Traumatic Stress Disorder in Scabies Patients: The Overlooked Part of a Global Outbreak.Cureus · 2025Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Vitiligo is the most common depigmentation disorder. This disease causes disfiguration and induces psychological burdens, leading to significantly impaired quality of life. Limited research about disease-related post-traumatic stress (PTS) has been conducted in vitiligo patients. Objective: To evaluate the prevalence, severity, and risk factors of post-traumatic stress in vitiligo patients. Methods: This case-control study was performed from January 2021 to April 2021. A survey questionnaire including baseline information, post-traumatic stress symptoms evaluation, life quality evaluation was conducted. According to the severity of post-traumatic stress symptoms, patients were grouped and compared. The logistic regression model was conducted to analyze the risk factors for post-traumatic stress disorder (PTSD). Results: A total of 337 patients were included. A 30.3% of vitiligo patients (102/337) in present cohort had PTS and 12.5% patients (42/337) were confirmed for developing into PTSD. The multivariate logistic regression revealed educational level<university (OR=2.32, 95% CI=1.97-2.93, P=0.003), vitiligo in face and neck (OR=2.65, 95% CI=2.08-3.12, P=0.008), vitiligo in feet and hands (OR=1.86, 95% CI=1.54-2.12, P<0.001) and surgical treatment (OR=3.53, 95% CI=3.12-4.02, P<0.001) were risk factors for PTSD. PTS severity was significantly associated with vitiligo disease activity score (rho=0.54, R2=0.29, P=0.002), vitiligo area scoring index score (r=0.55, R2=0.30, P=0.012), and dermatology life quality index score (r=0.61, R2=0.37, P=0.004). Conclusion: Vitiligo-related PTS is prevalent in vitiligo patients and causes psychological impairment. Dermatologists should realize and identify this condition carefully and offer proactive intervention to improve patients' quality of life.
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