Evidence map›Paper›PMID 35283584›Full record

ArticleBioinformation2021

Molecular docking and in vitro analysis of phytoextracts from B. serrata for antibacterial activities.

Ramsi Vakayil, Murugesan Anbazhagan, Gnanendra Shanmugam, Srinivasan Ramasamy, Maghimaa Mathanmohun

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Biomedical and Textile Applications ofNanomaterials (Basel, Switzerland) · 2022
    Article
  2. Antibiotics (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ramsi VakayilDepartment of Microbiology, Muthayammal College of Arts and Science, Rasipuram, Namakkal, Tamilnadu, India.
Murugesan AnbazhaganDepartment of Botany, Government Arts and Science College, Thiruvannamalai - 606603. Tamilnadu, India.
Gnanendra ShanmugamBioinformatics Division, Origene Biosolutions, Salem 16. Tamilnadu, India.
Srinivasan RamasamyMember secretary, Tamil Nadu State Council for Science & Technology, Chennai,Tamilnadu, India.
Maghimaa MathanmohunDepartment of Microbiology, Muthayammal College of Arts and Science, Rasipuram, Namakkal, Tamilnadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The bioactives of Boswellia serrata have a role in ulcer healing therapies. Eleven bioactive compounds were obtained by GC-MS among which Cholan-24-oic acid, 3,12-bis (acetyl oxy) has a high molecular weight of 490.6719 with a retention time of 26.729. Twenty wound samples were collected aseptically from the labs and hospitals in and around the Namakkal districts of Tamilnadu, India. The antibacterial potential of E.coli showed a maximum inhibition of 27 mm against Tetracycline at 30µg. The ethanolic extract of the B. serrata shows a susceptibility of 19mm towards E. coli at 60µg concentration in MIC. Molecular docking results show the binding energy of Cholan-24-oic acid, 3,12-bis(acetyloxy) -8.6 (kcal/mol) followed by Pyrene, hexadecahydro- -6.7 (kcal/mol), and 5(1H)- Azulenone, 2,4,6,7,8,8a-hexahydro-3,8-dimethyl-4-(1-methylethylidene)-, (8S-cis)- 6.4 (kcal/mol) for further consideration.

Indexed as

bioactive compoundsGCMSMolecular dockingPlant extract

Identifiers

PMID35283584
PMCPMC8882077
OpenAlexW4212964769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.