ReviewProceedings of the Japan Academy. Series B, Physical and biological sciences2022
Operating principles of the cerebral cortex as a six-layered network in primates: beyond the classic canonical circuit model.
Review in Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 23 citations in OpenAlex.
- An atlas of primate insular cortex reveals a signal-processing strategy in von Economo neurons.Nature cell biology · 2026Article
- The primate claustrum as a hub for precision weighting of prediction errors across the cortical hierarchy.PLoS biology · 2026Article
- Development of visual-stimulus reversal learning-memory in mice is dependent on social interaction.iScience · 2026Article
- High-precision cell-type mapping and annotation of single-cell spatial transcriptomics with STAMapper.Genome biology · 2025Article
- Complicated architecture of cortical microcircuit: a comprehensive review.Anatomical science international · 2025Review
- Characterizing positive and negative quantitative susceptibility values in the cortex following mild traumatic brain injury: a depth- and curvature-based study.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Mild traumatic brain injury increases cortical iron: evidence from individual susceptibility mapping.Brain communications · 2025Article
- Architecture and cellular composition of focal cortical dysplasia type II: qualitative review of histological studies.Frontiers in cellular neuroscience · 2025Review
- Multilayer network analysis across cortical depths in 7-T resting-state fMRI.Network neuroscience (Cambridge, Mass.) · 2025Article
- Multi-region processing during sleep for memory and cognition.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2025Review
- Multilayer Network Analysis across Cortical Depths in Resting-State 7T fMRI.bioRxiv : the preprint server for biology · 2024Article
- Article
- Dendritic Spines: Synaptogenesis and Synaptic Pruning for the Developmental Organization of Brain Circuits.Advances in neurobiology · 2023Article
- The inevitable inequality of cortical columns.Frontiers in systems neuroscience · 2022Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
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Abstract
The cerebral cortex performs its computations with many six-layered fundamental units, collectively spreading along the cortical sheet. What is the local network structure and the operating dynamics of such a fundamental unit? Previous investigations of primary sensory areas revealed a classic "canonical" circuit model, leading to an expectation of similar circuit organization and dynamics throughout the cortex. This review clarifies the different circuit dynamics at play in the higher association cortex of primates that implements computation for high-level cognition such as memory and attention. Instead of feedforward processing of response selectivity through Layers 4 to 2/3 that the classic canonical circuit stipulates, memory recall in primates occurs in Layer 5/6 with local backward projection to Layer 2/3, after which the retrieved information is sent back from Layer 6 to lower-level cortical areas for further retrieval of nested associations of target attributes. In this review, a novel "dynamic multimode module (D3M)" in the primate association cortex is proposed, as a new "canonical" circuit model performing this operation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.