Evidence map›Paper›PMID 35283376›Full record

ArticleInternal medicine (Tokyo, Japan)2022

Status Cataplecticus with Rapid Eye Movement Sleep Excess in Late-onset Narcolepsy Type 1.

Takashi Ando, Masakazu Wakai, Takashi Kanbayashi, Masahisa Katsuno

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Very late onset narcolepsy type 1: a case report and review of the literature.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Takashi AndoDepartment of Neurology, Nagoya University Graduate School of Medicine, Japan.
Masakazu WakaiDepartment of Sleep Medicine, Chutoen General Medical Center, Japan.
Takashi KanbayashiInternational Institute for Integrative Sleep Medicine, Tsukuba University, Japan.
Masahisa KatsunoDepartment of Neurology, Nagoya University Graduate School of Medicine, Japan.
Mie Chuo Medical Center · JPNagoya University · JPTsukuba International University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 57-year-old man presented with difficulty speaking and walking along with increased daytime somnolence. His symptoms fluctuated throughout the day but never completely disappeared. A neurological examination revealed mild dysarthria, limb weakness, and staggering gait. Polysomnography showed rapid eye movement (REM) sleep excess (55.0%). Multiple sleep latency tests revealed a mean sleep latency of zero minutes with sleep-onset REM periods in all naps. The Orexin-A concentration in the cerebrospinal fluid was low (50.8 pg/mL). Human leukocyte antigen testing demonstrated DQB1*0602 positivity. His neurological symptoms were relieved by clomipramine. Thus, he was diagnosed with late-onset narcolepsy type 1 with status cataplecticus.

Indexed as

NarcolepsySleep, REMClomipramineHLA AntigensHumansMaleMiddle AgedOrexinsClomipramineHLA AntigensOrexinscataplexynarcolepsyREM sleepsleep latencystatus cataplecticus

Identifiers

PMID35283376
PMCPMC9593136
OpenAlexW4220753752

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.