Evidence map›Paper›PMID 35282900›Full record

ArticleMedicina clinica2022

Mortality risk factors in patients with SARS-CoV-2 infection and atrial fibrillation: Data from the SEMI-COVID-19 registry.

Javier Azaña Gómez, Luis M Pérez-Belmonte, Manuel Rubio-Rivas, José Bascuñana, Raúl Quirós-López, María Luisa Taboada Martínez, Esther Montero Hernandez, Fernando Roque-Rojas, Manuel Méndez-Bailón, Ricardo Gómez-Huelgas and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Medicina clinica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Javier Azaña GómezServicio de Medicina Interna, Hospital Clínico San Carlos; Universidad Complutense de Madrid; Instituto de Investigación Sanitaria, Hospital Clínico San Carlos (IdISSC), Madrid, España.
Luis M Pérez-BelmonteServicio de Medicina Interna, Hospital Regional Universitario de Málaga; Instituto de Investigación Biomédica de Málaga (IBIMA), Universidad de Málaga (UMA), Málaga, España.
Manuel Rubio-RivasServicio de Medicina Interna, Hospital Universitario de Bellvitge-IDIBELL, L'Hospitalet de Llobregat (Barcelona), España.
José BascuñanaServicio de Medicina Interna, Hospital Universitario 12 de Octubre, Madrid, España.
Raúl Quirós-LópezServicio de Medicina Interna, Hospital Universitario Costa del Sol, Marbella (Málaga), España.
María Luisa Taboada MartínezServicio de Medicina Interna, Hospital Universitario de Cabueñes, Gijón (Asturias), España.
Esther Montero HernandezServicio de Medicina Interna, Hospital Universitario Puerta de Hierro, Majadahonda (Madrid), España.
Fernando Roque-RojasServicio de Medicina Interna, Hospital Universitario Infanta Cristina, Parla (Madrid), España.
Manuel Méndez-BailónServicio de Medicina Interna, Hospital Clínico San Carlos; Universidad Complutense de Madrid; Instituto de Investigación Sanitaria, Hospital Clínico San Carlos (IdISSC), Madrid, España. Electronic address: manuel.mendez@salud.madrid.org.
Ricardo Gómez-HuelgasServicio de Medicina Interna, Hospital Regional Universitario de Málaga; Instituto de Investigación Biomédica de Málaga (IBIMA), Universidad de Málaga (UMA), Málaga, España.
en nombre del grupo SEMI-COVID-19

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAtrial fibrillation and associated comorbidities pose a risk factor for mortality, morbidity and development of complications in patients admitted for COVID-19.

objectivesTo describe the clinical, epidemiological, radiological and analytical characteristics of patients with atrial fibrillation admitted for COVID-19 in Spain. Secondarily, we aim to identify those variables associated with mortality and poor prognosis of COVID-19 in patients with atrial fibrillation.

methodsRetrospective, observational, multicenter, nationwide, retrospective study of patients hospitalized for COVID-19 from March 1 to October 1, 2020. Data were obtained from the SEMI-COVID-19 Registry of the Spanish Society of Internal Medicine (SEMI) in which 150 Spanish hospitals participate.

resultsBetween March 1 and October 1, 2020, data from a total of 16,461 patients were entered into the SEMI-COVID-19 registry. 1816 (11%) had a history of atrial fibrillation and the number of deaths among AF patients amounted to 738 (41%). Regarding clinical characteristics, deceased patients were admitted with a higher heart rate (88.38 vs. 84.95; P>0.01), with a higher percentage of respiratory failure (67.2 vs. 20.1%; P<0.01) and high tachypnea (58 vs. 30%; P<0.01). The comorbidities that presented statistically significant differences in the deceased group were: age, hypertension and diabetes with target organ involvement. There was also a higher prevalence of a history of cardiovascular disease in the deceased. On multivariate analysis, DOACs treatment had a protective role for mortality (OR: 0.597; CI: 0.402-0.888; P=0.011).

conclusionsPrevious treatment with DOACs and DOACs treatment during admission seem to have a protective role in patients with atrial fibrillation, although this fact should be verified in prospective studies.

Indexed as

Atrial FibrillationCOVID-19HumansProspective StudiesRegistriesRetrospective StudiesRisk FactorsSARS-CoV-2AnticoagulaciónAnticoagulationAtrial fibrillationCOVID-19Factor de riesgoFibrilación auricularHospitalizaciónHospitalizationMortalidadMortalityRisk factor

Identifiers

PMID35282900
PMCPMC8908017

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.