Evidence map›Paper›PMID 35282821›Full record

ArticleBMC medical imaging2022

Automated detection of pulmonary embolism from CT-angiograms using deep learning.

Heidi Huhtanen, Mikko Nyman, Tarek Mohsen, Arho Virkki, Antti Karlsson, Jussi Hirvonen

Abstract read
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Article in BMC medical imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  6. Deep learning-based segmentation of acute pulmonary embolism in cardiac CT images.International journal of computer assisted radiology and surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Heidi HuhtanenDepartment of Radiology, University of Turku and Turku University Hospital, Turku, Finland. hejohuh@utu.fi.
Mikko NymanDepartment of Radiology, University of Turku and Turku University Hospital, Turku, Finland.
Tarek MohsenReaktor Innovations Oy, Helsinki, Finland.
Arho VirkkiAuria Clinical Informatics, Turku University Hospital, Turku, Finland.
Antti KarlssonAuria Biobank, Turku University Hospital, University of Turku, Turku, Finland.
Jussi HirvonenDepartment of Radiology, University of Turku and Turku University Hospital, Turku, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to develop and evaluate a deep neural network model in the automated detection of pulmonary embolism (PE) from computed tomography pulmonary angiograms (CTPAs) using only weakly labelled training data.

methodsWe developed a deep neural network model consisting of two parts: a convolutional neural network architecture called InceptionResNet V2 and a long-short term memory network to process whole CTPA stacks as sequences of slices. Two versions of the model were created using either chest X-rays (Model A) or natural images (Model B) as pre-training data. We retrospectively collected 600 CTPAs to use in training and validation and 200 CTPAs to use in testing. CTPAs were annotated only with binary labels on both stack- and slice-based levels. Performance of the models was evaluated with ROC and precision-recall curves, specificity, sensitivity, accuracy, as well as positive and negative predictive values.

resultsBoth models performed well on both stack- and slice-based levels. On the stack-based level, Model A reached specificity and sensitivity of 93.5% and 86.6%, respectively, outperforming Model B slightly (specificity 90.7% and sensitivity 83.5%). However, the difference between their ROC AUC scores was not statistically significant (0.94 vs 0.91, p = 0.07).

conclusionsWe show that a deep learning model trained with a relatively small, weakly annotated dataset can achieve excellent performance results in detecting PE from CTPAs.

Indexed as

Deep LearningPulmonary EmbolismAngiographyHumansRetrospective StudiesTomography, X-Ray ComputedArtificial intelligenceAutomated detectionDeep learningEmergency radiologyPulmonary embolism

Identifiers

PMID35282821
PMCPMC8919639

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.