Evidence map›Paper›PMID 35282769›Full record

ArticleBioengineered2022

The NOP14 nucleolar protein suppresses the function and stemness of melanoma stem-like cells through Wnt/beta-catenin signaling inactivation.

Jingrong Li, Ruihua Fang, Jiang Wu, Yuan Si, Jingzhu Bai, Qi Wang

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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  8. Caudatin Inhibits the Proliferation, Invasion, and Glycolysis of Osteosarcoma Cells via the Wnt/Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jingrong LiDepartment of Dermatology, Guangzhou First People's Hospital, Guangzhou, Guangdong Province, China.
Ruihua FangDepartment of Dermatology, Guangzhou First People's Hospital, Guangzhou, Guangdong Province, China.
Jiang WuDepartment of Dermatology, Guangzhou First People's Hospital, Guangzhou, Guangdong Province, China.
Yuan SiDepartment of Dermatology, Guangzhou First People's Hospital, Guangzhou, Guangdong Province, China.
Jingzhu BaiDepartment of Dermatology, Guangzhou First People's Hospital, Guangzhou, Guangdong Province, China.
Qi WangDepartment of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, China.
Guangzhou Medical University · CNGuangzhou First People's Hospital · CNNanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer stem cells (CSCs) are closely related to tumor occurrence, development, metastasis, drug resistance, and recurrence. The role of CSCs in melanoma is poorly understood. Our previous studies suggested that the NOP14 nucleolar protein (NOP14) is involved in melanoma pathogenesis regulation. Importantly, NOP14 overexpression inhibits the Wnt/beta (β)-catenin signaling pathway, an important mechanism regulating CSCs stemness. Therefore, in this study, we aimed to explore the role of NOP14 in the stemness and function of CSCs in melanoma

Indexed as

MelanomaWnt Signaling Pathwaybeta CateninCell Line, TumorCell ProliferationEndothelial CellsGene Expression Regulation, NeoplasticHumansNeoplastic Stem CellsNuclear Proteinsbeta CateninNOP14 protein, humanNuclear ProteinsCSCs in melanomaNOP14stemnesswnt/beta-catenin signaling

Identifiers

PMID35282769
PMCPMC9208496
OpenAlexW4220801519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.