Evidence map›Paper›PMID 35282665›Full record

ArticleCardiovascular diagnosis and therapy2022

Prevalence and real-world management of NSTEMI with multivessel disease.

Angus A W Baumann, Rosanna Tavella, Tracy M Air, Aashka Mishra, Nicholas J Montarello, Margaret Arstall, Chris Zeitz, Matthew I Worthley, John F Beltrame, Peter J Psaltis

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular diagnosis and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Angus A W BaumannDepartment of Cardiology, Central Adelaide Local Health Network (CALHN), Adelaide, Australia.
Rosanna TavellaDepartment of Cardiology, Central Adelaide Local Health Network (CALHN), Adelaide, Australia.
Tracy M AirAdelaide Medical School, The University of Adelaide, Adelaide, Australia.
Aashka MishraDepartment of Cardiology, Central Adelaide Local Health Network (CALHN), Adelaide, Australia.
Nicholas J MontarelloDepartment of Cardiology, Central Adelaide Local Health Network (CALHN), Adelaide, Australia.
Margaret ArstallAdelaide Medical School, The University of Adelaide, Adelaide, Australia.
Chris ZeitzDepartment of Cardiology, Central Adelaide Local Health Network (CALHN), Adelaide, Australia.
Matthew I WorthleyDepartment of Cardiology, Central Adelaide Local Health Network (CALHN), Adelaide, Australia.
John F BeltrameDepartment of Cardiology, Central Adelaide Local Health Network (CALHN), Adelaide, Australia.
Peter J PsaltisDepartment of Cardiology, Central Adelaide Local Health Network (CALHN), Adelaide, Australia.
University of Adelaide · AUWomen's and Children's Health Network · AUCentral Adelaide Local Health NetworkQueen Elizabeth Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Non-ST elevation myocardial infarction (NSTEMI) has higher post-discharge mortality than ST-elevation myocardial infarction (STEMI). Prognosis worsens in those with multivessel coronary disease (MVD). However, information about the prevalence and extent of MVD in NSTEMI is limited, in turn limiting insights into optimal treatment strategies. This study aimed to define the prevalence and extent of MVD, preferred treatment strategies and the predictors of MVD in a real-world NSTEMI population. Methods: The Coronary Angiogram Database of South Australia (CADOSA) was used to identify consecutive patients presenting to major teaching hospitals with NSTEMI between 2012 and 2016. Obtaining clinical and angiographic details, patients were stratified by the number of significantly diseased vessels (0,1,2,3-VD), defined by a stenosis of ≥70%, or ≥50% in the left main coronary artery. Data was analysed retrospectively. Results: The prevalence of MVD (2- or 3-VD) was 42% amongst 3,722 NSTEMI presentations. Multivariate logistic regression modelling showed age, male gender, diabetes, dyslipidaemia and prior myocardial infarction predicted MVD over 1-VD or 0-VD. Percutaneous coronary intervention (PCI) was performed in 42% of patients with MVD. This comprised 61% of 2-VD patients and only 22% of 3-VD patients, with 24% and 66% of each group referred for coronary bypass grafting, respectively. Among MVD patients treated with PCI, 76% had their culprit lesion treated alone in the index admission. Conclusions: In this NSTEMI cohort, over 40% had MVD. Notably, a minority of patients with MVD undergoing PCI received multivessel revascularisation. This real-world practice emphasises that further evaluation is required to determine whether complete revascularisation is beneficial in NSTEMI, as reported for STEMI.

Indexed as

coronary artery bypass graftingcoronary revascularisationmultivessel coronary artery diseaseNon-ST elevation myocardial infarction (NSTEMI)percutaneous coronary intervention

Identifiers

PMID35282665
PMCPMC8898694
OpenAlexW4213041595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.