Evidence map›Paper›PMID 35282646›Full record

ArticleInternational journal of general medicine2022

Pan-Cancer Analyses Confirmed the Ferroptosis-Related Gene

Yi Lin, Yubing Dong, Wanyu Liu, Xingyun Fan, Ying Sun

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  8. Article
  9. Metabolic Regulation of Ferroptosis in Breast Cancer.International journal of molecular sciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yi LinDepartment of Anesthesiology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, 116011, People's Republic of China.
Yubing DongDepartment of Internal Medicine, First affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, 116011, People's Republic of China.
Wanyu LiuDepartment of Internal Medicine, First affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, 116011, People's Republic of China.
Xingyun FanDepartment of Internal Medicine, First affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, 116011, People's Republic of China.
Ying SunDepartment of Digestive Endoscopy, First Affiliated Hospital of Dalian Medical University., Dalian, 116011, Liaoning Province, People's Republic of China.
First Affiliated Hospital of Dalian Medical University · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Ferroptosis is an iron-dependent and reactive oxygen species (ROS)-reliant form of cell death, exhibiting cellular, molecular, and gene-level characteristics distinct from those of necrosis, autophagy, apoptosis, and pyroptosis. Solute carrier family 7 member 11 ( Patients and Methods: Transcriptomic data for 6313 tumors and normal samples across 20 cancer types were acquired from The Cancer Genome Atlas (TCGA) database. Besides, we presented a novel bioinformatics pipeline that uncovered the impacts of Results: Conclusion: The comprehensive pan-cancer analyses identified

Indexed as

drug sensitivityferroptosisimmunotherapypan-cancerSLC7A11

Identifiers

PMID35282646
PMCPMC8906875
OpenAlexW4214828382

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.