Evidence map›Paper›PMID 35282522›Full record

ArticleCureus2022

COVID-19 Infection and Guillain-Barre Syndrome: A Case Series.

Kendal Carpenter, Ayman Iqbal, Romil Singh, Keerti Deepika, Thoyaja Koritala, Nitesh Jain, Ram Sanjeev Alur, Ramesh Adhikari, Vishwas S Mellekate

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 2 countries.

Kendal CarpenterNeurology, Union Health, Terre Haute, USA.
Ayman IqbalInternal Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, PAK.
Romil SinghCritical Care, Allegheny Health Network, Pittsburgh, USA.
Keerti DeepikaHealth Equity and Inclusion, Nemours Alfred I. duPont Hospital for Children, Wilmington, USA.
Thoyaja KoritalaInternal Medicine, Mayo Clinic, Mankato, USA.
Nitesh JainPulmonary and Critical Care Medicine, Mayo Clinic, Mankato, USA.
Ram Sanjeev AlurInternal Medicine, Marion Veterans Affairs Medical Center, Marion, USA.
Ramesh AdhikariHospital Medicine, Franciscan Health, Lafayette, USA.
Vishwas S MellekateNeurology, Union Health, Terre Haute, USA.
Union Hospital · USAlfred I. duPont Hospital for Children · USAllegheny Health Network · USBrown University · USDow University of Health Sciences · PKMayo Clinic Health System · USMayo Clinic in Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) pandemic brought about an unprecedented time. Multiple systemic complications have been recognized with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as it can do much more than affect the respiratory system. One of the intriguing neurological complications is Guillain-Barre syndrome (GBS). We reviewed three cases in which patients presented with GBS following COVID-19 infection. All three cases had positive lumbar puncture results with albumino-cytological dissociation. Each patient was treated with plasmapheresis and improved clinically. Although an exact causal relationship between COVID-19 and GBS cannot be drawn from this case series alone, it signifies the importance of this complication. It warrants further studies to establish the causal relationship. One should have a high suspicion for acute inflammatory demyelinating polyneuropathy (AIDP) in patients presenting with acute onset of ascending weakness following COVID-19 infection.

Indexed as

acute inflammatory demyelinating polyradiculoneuropathyalbuminocytologic dissociationcovid-19cytokine stormgullian-barre syndromemyasthenia gravisneurological complication

Identifiers

PMID35282522
PMCPMC8906908
OpenAlexW4212950499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.