Evidence map›Paper›PMID 35282475›Full record

ArticleActa clinica Croatica2022

ABO BLOOD GROUP GENOTYPES IN WOMEN WITH BREAST CANCER.

Tamara Bezek, Jasna Bingulac-Popović, Dinko Bagatin, Roberta Petlevski, Irena Jukić

Open access · diamondAbstract read
In one paragraph

Article in Acta clinica Croatica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Age-Related Trends in Breast Cancer Incidence.International journal of breast cancer · 2026
    Article
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tamara Bezek1Molecular Diagnostics Department, Croatian Institute of Transfusion Medicine, Zagreb, Croatia; 2Bagatin Clinic, Zagreb, Croatia; 3Faculty of Dental Medicine and Health in Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 4Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia; 5Medical Department, Croatian Institute of Transfusion Medicine, Zagreb, Croatia; 6Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
Jasna Bingulac-Popović1Molecular Diagnostics Department, Croatian Institute of Transfusion Medicine, Zagreb, Croatia; 2Bagatin Clinic, Zagreb, Croatia; 3Faculty of Dental Medicine and Health in Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 4Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia; 5Medical Department, Croatian Institute of Transfusion Medicine, Zagreb, Croatia; 6Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
Dinko Bagatin1Molecular Diagnostics Department, Croatian Institute of Transfusion Medicine, Zagreb, Croatia; 2Bagatin Clinic, Zagreb, Croatia; 3Faculty of Dental Medicine and Health in Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 4Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia; 5Medical Department, Croatian Institute of Transfusion Medicine, Zagreb, Croatia; 6Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
Roberta Petlevski1Molecular Diagnostics Department, Croatian Institute of Transfusion Medicine, Zagreb, Croatia; 2Bagatin Clinic, Zagreb, Croatia; 3Faculty of Dental Medicine and Health in Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 4Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia; 5Medical Department, Croatian Institute of Transfusion Medicine, Zagreb, Croatia; 6Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
Irena Jukić1Molecular Diagnostics Department, Croatian Institute of Transfusion Medicine, Zagreb, Croatia; 2Bagatin Clinic, Zagreb, Croatia; 3Faculty of Dental Medicine and Health in Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 4Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia; 5Medical Department, Croatian Institute of Transfusion Medicine, Zagreb, Croatia; 6Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
Croatian Institute of Transfusion Medicine · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ABO blood group is a risk factor for several cancers, but it is not clear yet whether the risk of breast cancer is greater in particular ABO blood type carriers. The aim of this case-control study was to examine the correlation between ABO blood group genotypes, estrogen receptor (ER), progesterone receptor (PR) and HER2 status as tumor grade markers (I-III), and the occurrence of breast cancer. The research included 59 patients with invasive breast cancer and 80 asymptomatic, healthy women, blood donors. Genomic DNA was isolated using QIAampDNA Blood Mini Kit (QIAGEN, Germany). Genotyping was performed using in-house polymerase chain reaction with sequence-specific primers (PCR-SSP) method. Comparison of genotypes and phenotypes of ABO blood groups between patients and control group yielded p>0.05. There was no statistical significance of correlation between ABO genotypes/phenotypes in either patient group or control group. Testing the significance of different tumor grade occurrence, and ER, PR and HER2/neu status showed no statistical significance ​​in the occurrence of a particular tumor grade, or in ER, PR and HER2/neu status as tumor markers in O1A1 genotype compared to non-O1A1 genotypes. Our study results confirmed that there was no correlation between ABO blood type genotypes/phenotypes and breast cancer in study groups.

Indexed as

Breast NeoplasmsABO Blood-Group SystemCase-Control StudiesErb-b2 Receptor Tyrosine KinasesFemaleGenotypeHumansABO Blood-Group SystemErb-b2 Receptor Tyrosine KinasesABO blood groupsABO genotypesABO phenotypesBreast cancer

Identifiers

PMID35282475
PMCPMC8907954
OpenAlexW4220704845

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.