Evidence map›Paper›PMID 35282446›Full record

ReviewFrontiers in endocrinology2022

Gut and Vaginal Microbiomes in PCOS: Implications for Women's Health.

Yuanyuan Gu, Guannan Zhou, Fangyue Zhou, Yao Li, Qiongwei Wu, Hongyu He, Yi Zhang, Chengbin Ma, Jingxin Ding, Keqin Hua

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
16.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 95 citations in OpenAlex.

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  16. The Vaginal Microbiome and Reproductive Health in Adolescents and Adults.Journal of pediatric and adolescent gynecology · 2025
    Review
  17. Review
  18. Effects of vaginal microbiota onMicrobiology spectrum · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Yuanyuan GuChangning Maternity and Infant Health Hospital, East China Normal University, Shanghai, China.
Guannan ZhouDepartment of Gynecology, The Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Fangyue ZhouThe International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yao LiDepartment of Urology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, China.
Qiongwei WuChangning Maternity and Infant Health Hospital, East China Normal University, Shanghai, China.
Hongyu HeDepartment of Intensive Care Unit, Zhongshan Hospital, Fudan University, Shanghai, China.
Yi ZhangChangning Maternity and Infant Health Hospital, East China Normal University, Shanghai, China.
Chengbin MaChangning Maternity and Infant Health Hospital, East China Normal University, Shanghai, China.
Jingxin DingDepartment of Gynecology, The Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Keqin HuaDepartment of Gynecology, The Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Obstetrics and Gynecology Hospital of Fudan University · CNEast China Normal University · CNFudan University · CNInternational Peace Maternity & Child Health Hospital · CNSecond Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PCOS is defined as a kind of endocrine and metabolic disorder which affects females at reproductive ages, is becoming much more common, nowadays. Microbiomes are known as microorganisms that inhabit the body to play a vital role in human health. In recent years, several basic and clinical studies have tried to investigate the correlation between the reproductive health/disorder and microbiomes (gut microbiomes and vaginal microbiomes). However, the mechanism is still unclear. In this review, we reviewed the relationship between PCOS and microbiomes, including gut/vaginal microbiomes compositions in PCOS, mechanism of microbiomes and PCOS, and then collectively focused on the recent findings on the influence of microbiomes on the novel insight regarding the therapeutic strategies for PCOS in the future clinical practice.

Indexed as

Gastrointestinal MicrobiomeMicrobiotaPolycystic Ovary SyndromeFemaleHumansReproductionWomen's Healthgut microbiomesmechanismPCOS (polycystic ovarian syndrome)therapeuticsvaginal microbiomes

Identifiers

PMID35282446
PMCPMC8905243
OpenAlexW4214654924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.