Evidence map›Paper›PMID 35282429›Full record

ReviewFrontiers in endocrinology2022

Antidiabetic Phytochemicals From Medicinal Plants: Prospective Candidates for New Drug Discovery and Development.

Safaet Alam, Md Moklesur Rahman Sarker, Taposhi Nahid Sultana, Md Nafees Rahman Chowdhury, Mohammad A Rashid, Nusrat Islam Chaity, Chao Zhao, Jianbo Xiao, Elsayed E Hafez, Shah Alam Khan and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 2 pooled it
41.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 2 syntheses or guidelines pooled it, 318 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Antidiabetic Properties ofLife (Basel, Switzerland) · 2026
    Review
  7. Review
  8. Article
  9. Peel of Pomegranate Fruit (Current issues in molecular biology · 2026
    Article
  10. Review
  11. Protective Effects of Pomiferin on Aluminum Chloride-induced Memory Impairment: Evidence from Behavioral, Biochemical, and Insilico Studies.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2026
    Article
  12. Article
  13. Phytoconstituents Analysis andTropical life sciences research · 2026
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Profiling and cheminformatics bioprospection of curcurbitacin I and momordin Ic fromJournal of enzyme inhibition and medicinal chemistry · 2025
    Article
  19. Review
  20. Article

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 6 countries.

Safaet AlamDepartment of Pharmacy, State University of Bangladesh, Dhaka, Bangladesh.
Md Moklesur Rahman SarkerDepartment of Pharmacy, State University of Bangladesh, Dhaka, Bangladesh.
Taposhi Nahid SultanaDepartment of Pharmacy, University of Asia Pacific, Dhaka, Bangladesh.
Md Nafees Rahman ChowdhuryDepartment of Pharmacy, University of Dhaka, Dhaka, Bangladesh.
Mohammad A RashidDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka, Bangladesh.
Nusrat Islam ChaityDepartment of Pharmacy, State University of Bangladesh, Dhaka, Bangladesh.
Chao ZhaoCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou, China.
Jianbo XiaoDepartment of Analytical Chemistry and Food Science, Faculty of Food Science and Technology, University of Vigo, Vigo, Spain.
Elsayed E HafezPlant Protection and Biomolecular Diagnosis Department, ALCRI (Arid Lands Cultivation Research Institute), City of Scientific Research and Technological Applications, Alexandria, Egypt.
Shah Alam KhanCollege of Pharmacy, National University of Science & Technology, Muscat, Oman.
Isa Naina MohamedPharmacology Department, Medicine Faculty, Universiti Kebangsaan Malaysia (The National University of Malaysia), Kuala Lumpur, Malaysia.
State University of Bangladesh · BDUniversity of Dhaka · BDCity of Scientific Research and Technological Applications · EGFujian Agriculture and Forestry University · CNMuscat College · OMNational University of Malaysia · MYUniversidade de Vigo · ESUniversity of Asia Pacific · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes, a chronic physiological dysfunction affecting people of different age groups and severely impairs the harmony of peoples' normal life worldwide. Despite the availability of insulin preparations and several synthetic oral antidiabetic drugs, there is a crucial need for the discovery and development of novel antidiabetic drugs because of the development of resistance and side effects of those drugs in long-term use. On the contrary, plants or herbal sources are getting popular day by day to the scientists, researchers, and pharmaceutical companies all over the world to search for potential bioactive compound(s) for the discovery and development of targeted novel antidiabetic drugs that may control diabetes with the least unwanted effects of conventional antidiabetic drugs. In this review, we have presented the prospective candidates comprised of either isolated phytochemical(s) and/or extract(s) containing bioactive phytoconstituents which have been reported in several

Indexed as

Diabetes MellitusPlants, MedicinalDrug DiscoveryHumansHypoglycemic AgentsPhytochemicalsProspective StudiesHypoglycemic AgentsPhytochemicalsantidiabeticantihyperglycemicbioactive compounddiabetes mellitusdrug developmentdrug discoveryphytochemicalphytomedicine

Identifiers

PMID35282429
PMCPMC8907382
OpenAlexW4213431219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.